[Effect of polydatin on miR-214 expression and liver function in ApoE-/- mice].

Objective: To study the effect of polydatin on the expression level of miR-214 and liver function in atherosclerotic mice.

Methods: Forty male ApoE(-/-) mice were randomly allocated into 4 groups (n=10), namely the model group, low- and high-dose polydatin groups, and simvastin group, with 10 male C57BL/6J mice serving as the normal control group. Mouse models of atherosclerosis were established by feeding the ApoE(-/-) mice with a high-fat diet.