[The experimental study of creating a new rat scarring model by inserting absorbable gelatin sponge into rats' excisional wounds].

Objective: To explore the possibility of creating a rat new scar model by inserting gelatin sponge into rat excisional wounds.

Methods: Two full-thickness wounds were created in each of total 49 SD rats. In the Experimental group (n = 19), a regular incisional wound (1 cm) was created on the left side, and an excisional wound of 1.

Trauma and pulmonary thromboembolism: an experimental study on their correlation.

Objective: To investigate the correlation between trauma and pulmonary thromboembolism.

Methods: Comminuted fractures and extensive soft-tissue contusion at both hind limbs were made by a falling weight from a height in 16 rabbits. Lung perfusion scanning was performed to obtain the radioactivity counts before trauma, at 1 h, 48 h and 96 h after trauma.

[Overexpression of truncated type II transforming growth factor-beta receptor in dermal fibroblasts].

Objective: To study the effect of overexpression of truncated type II TGF-beta receptor on transforming growth factor-beta 1(TGF-beta 1) autoproduction in normal dermal fibroblasts.

Methods: In vitro cultured dermal fibroblasts were treated with recombinant human TGF-beta 1(rhTGF-beta 1) (5 ng/ml) or recombinant adenovirus containing truncated type II TGF-beta receptor gene (50 pfu/cell). Their effects on regulating gene expression of TGF-beta 1 were observed with Northern blotting.