Secondary Metabolites with Agricultural Antagonistic Potentials from , a Marine-Derived Entomopathogenic Fungus.

Soil-borne pathogens and weeds could synergistically affect vegetable growth and result in serious losses. The investigation of antagonistic metabolites from a marine-derived entomopathogenic fungus, , obtained polyhydroxy steroid (), tricyclic diterpenoid (), isaridin (), and destruxin cyclodepsipeptides (). The structures and absolute configurations of new were elucidated by extensive spectroscopic and X-ray crystallographic analyses, as well as electronic circular dichroism (ECD) calculations.

Herbicidal Polyketides and Diketopiperazine Derivatives from .

Herbicidal activity-guided isolation from the fermentation extract of had obtained two herbicidal series of polyketides (-) and diketopiperazine derivatives (-), especially including three novel polyketides (-). The structures and absolute configurations of new polyketides - were elucidated by extensive spectroscopic analyses, as well as comparisons between measured and calculated ECD spectra. Novel polyketides - and known , all bearing the heptaketide skeleton with a -fused decalin ring of 8-CH substitution, could significantly inhibit the radicle growth of seedlings with a dose-dependent relationship.