Publications by authors named "Ze-Bing Guan"

We aimed to characterize the clinical significance of epigenetic loss of death-associated protein kinase (DAPK) gene function through promoter methylation in the development and prognosis of lymphoma. PubMed, Web of Science and ProQuest databases were searched for relevant studies. Twelve studies involving 709 patients with lymphoma were identified.

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Objective: To explore the expression and clinical significance of Semaphorin4D (Sema4D) mRNA in peripheral blood lymphocyte, Sema4D on platelet surface, soluble Sema4D (sSema4D) in plasma in patients with cerebral infarction.

Methods: Taking 299 patients with cerebral infarction as the case group while 195 healthy adults as the control group. The mRNA expression of Sema4D was detected by Real-time PCR, and Sema4D expression on platelet by flow cytometry, sSema4D by ELISA.

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Article Synopsis
  • The study aimed to investigate how protein Z (PZ) levels change in patients with cardio-cerebral thrombotic diseases and their relationship with factor X (FX) levels.
  • Results showed that PZ levels were significantly lower in patients with acute ischemic stroke (AIS) and acute myocardial infarction (AMI) compared to healthy individuals, while FX levels were elevated in these patient groups.
  • The decrease in PZ was linked to the severity and recurrence of the diseases, with age also playing a role in PZ levels, but no significant correlation was found with gender.
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