Publications by authors named "Ze Ou"

Article Synopsis
  • Somatosensory evoked potentials (SEPs) can predict poor outcomes in hypoxic-ischemic coma, especially when cortical responses (N20s) are absent, but the presence of bilateral N20s doesn't guarantee good outcomes.
  • The study created a new measurement called HFO evoked to spontaneous ratios (HFO-ESRs) to help better identify patients with potential for recovery among those with bilaterally present N20s.
  • Results showed that adding HFO-ESRs improved prediction accuracy for better Glasgow Coma Scale (GCS) outcomes, achieving 85% specificity with advanced modeling, indicating the need for further research to confirm these findings in different cases.
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Objective: Here we investigate the ability of low-intensity ultrasound (LIUS) applied to the spinal cord to modulate the transmission of motor signals.

Methods: Male adult Sprague-Dawley rats (n = 10, 250-300 g, 15 weeks old) were used in this study. Anesthesia was initially induced with 2% isoflurane carried by oxygen at 4 L/min via a nose cone.

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Cardiac arrest (CA) remains the leading cause of coma, and early arousal recovery indicators are needed to allocate critical care resources properly. High-frequency oscillations (HFOs) of somatosensory evoked potentials (SSEPs) have been shown to indicate responsive wakefulness days following CA. Nonetheless, their potential in the acute recovery phase, where the injury is reversible, has not been tested.

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