Development and psychometric evaluation of an instrument measuring ambulance nurses' adherence and attitudes to acute chest pain guidelines.

Background: Effective prehospital care for acute chest pain critically relies on ambulance nurses' adherence to clinical guidelines. However, current adherence is inadequate, with no instruments available to improve the situation. Therefore, this study aimed to develop and psychometrically evaluate an instrument measuring ambulance nurses' adherence to and attitudes towards acute chest pain guidelines, and to adapt and test the Attitudes Regarding Practice Guidelines instrument for measuring general attitudes towards guidelines.

Using a participatory action research approach to explore, understand and evaluate well-being among children living in socially deprived areas in Southern Sweden: a study protocol.

Introduction: Research suggests that participating in after-school leisure activities has been related to promoting health, well-being and safety among children living in disadvantaged neighbourhoods. The United Nations Child Rights Convention emphasises the inclusion of children in decisions that concern them. However, children seldom are involved in designing implementing and evaluating health promotional environments.

Diabetes type 2 prevalence is rising among young residents in Malmö, Sweden.

Aim: Type 2 diabetes is becoming more prevalent in many parts of the world. Malmö's population has increased in recent years mainly because of migration from other parts of Sweden and the world in addition to increased birth rates. We aimed to explore diabetes prevalence in Malmö in 2011-2018 as well as the achieved treatment targets for selected diabetes-related outcomes.

Changes in daily nursing needs and self-care capability of people with diabetes after in-hospital treatment for foot complications: A descriptive study.

Aim: A limited number of studies discuss the changes in patients' self-care skills and needs for assisted self-care after discharge from in-patient treatment due to diabetes foot ulcer-related complications. The aim of this study was to examine the ability to perform self-care and needs for assisted nursing interventions at hospital discharge, compared to pre-admission, for people with diabetes admitted and treated for foot ulcer-related complications.

Design: Retrospective patient record study.

Molecular Classification Outperforms Histologic Classification in Prognostication of High-grade Endometrial Carcinomas With Undifferentiated and Sarcomatous Components.

Since the establishment of 4 molecular subgroups of endometrial carcinoma (EC), there has been significant interest in understanding molecular classification in the context of histologic features and diagnoses. ECs with undifferentiated, spindle, and/or sarcomatous components represent a diagnostically challenging subset of tumors with overlapping clinical and histologic features. We examined the clinicopathologic, morphologic, immunohistochemical, and molecular features of these tumors identified in our institutions' pathology databases using immunohistochemistry and targeted sequencing.

The inner tube effect.

We describe a novel size illusion in which targets appear to either shrink or grow when enclosed within a narrow tube. The direction of size change is determined by the contrast step between display elements. We first noticed this effect in the context of the dynamic "rocking line" illusion (RLI), but it can also be easily seen in completely static displays.

Blood pressure cut-offs to diagnose impending hypertensive emergency depend on previous hypertension-mediated organ damage and comorbid conditions.

Background Hypertensive emergencies (HTN-E) are important due to a high risk of mortality. However, a sudden increase in blood pressure (BP) can damage target organs before the BP reaches cut-offs to diagnose HTN-E. We (i) analyse HTN guidelines for recommendations of treatment individualization, such as adjusting BP cut-offs for hypertensive urgency or impending HTN-E according to patient's susceptibility to complications (because of previous hypertension-mediated organ damage [HMOD], cardiovascular events and comorbid conditions), and (ii) provide a rationale for the inclusion of patient's susceptibility in protocols for treatment of acute HTN-E.

CHRNA6 RNA In Situ Hybridization Is a Useful Tool for the Diagnosis of Extraskeletal Myxoid Chondrosarcoma.

Extraskeletal myxoid chondrosarcoma (EMC) is an uncommon mesenchymal neoplasm characteristically composed of uniform-appearing round to spindle-shaped cells with eosinophilic cytoplasm and abundant myxoid extracellular matrix. Although the majority of cases harbor a pathognomonic t(9;22) translocation that fuses EWSR1 with the orphan nuclear receptor NR4A3, there are less common variants that partner NR4A3 with TAF15, TCF12, or TFG. By immunohistochemistry, EMC has features of both cartilaginous and neuroendocrine differentiation, as evidenced by inconsistent expression of S100 protein and synaptophysin or INSM1, respectively, in a subset of cases.

Contingent capture by color is sensitive to categorical color perception.

Contingent capture (CC) theory postulates that attention can only be captured by top-down matching stimuli. Although the contingent capture of attention is a well-known and thoroughly studied phenomenon, there is still no consensus on the characteristics of the top-down template which guides the search for colors. We tried to replicate the classical contingent capture effect on color (Experiment 1) and then added linguistic processing to this perceptual effect (Experiment 2).

Detection of FOXL2 C134W Mutation Status by a Novel BaseScope In Situ Hybridization Assay is Highly Sensitive and Specific for Adult Granulosa Cell Tumors.

Adult granulosa cell tumors (AGCTs) are a molecularly distinct group of malignant ovarian sex cord-stromal tumors (SCSTs) characterized by a nearly ubiquitous c.402C>G/p.C134W mutation in FOXL2 (hereafter referred to as "C134W").

Calcium messages in flagella are faster than messenger particles.

Calcium is one of the most versatile messengers for intracellular signaling. In the case of cilia and flagella calcium has the central role in transfer of communications between extracellular stimuli and intracellular formation of frequency modulated signal and their deciphering by target proteins. In this paper, the diffusion of fluorescently or otherwise tagged and un-tagged Ca particles is analyzed by solving the system of pertaining reaction-diffusion equations.

Social relations and mental ill-health among newly arrived refugees in Sweden: A cross-sectional study.

Background: Previous research indicates that social relations have an impact on the well-being of refugees and that well-being is important for effective integration into the host country. Few studies in Sweden have, to the best of our knowledge, looked at the association between social relations and mental ill-health among newly arrived refugees. The aim is to investigate what effect social relations have on the mental health of newly arrived refugees in the south of Sweden.

Diagnostic utility of FOXO1 immunohistochemistry for rhabdomyosarcoma classification.

Aims: Rhabdomyosarcomas currently are classified into one of four subtypes (alveolar, embryonal, spindle cell/sclerosing, or pleomorphic) according to their morphological, immunohistochemical, and molecular genetic features. The alveolar subtype is characterised by a recurrent translocation involving PAX3 or PAX7 and FOXO1; identification of this translocation is important for appropriate classification and prognostication. In this study, we aimed to explore the diagnostic utility of FOXO1 immunohistochemistry for rhabdomyosarcoma classification.

Empirical evaluation of computational models of lightness perception.

Lightness of a surface depends not only on its physical characteristics, but also on the properties of the surrounding context. As a result, varying the context can significantly alter surface lightness, an effect exploited in many lightness illusions. Computational models can produce outcomes similar to human illusory percepts, allowing for demonstrable assessment of the applied mechanisms and principles.

Risk for mental illness following exposure to violence and threats among newly arrived refugees.

Objective: There is an association between pre-migration exposure to threats and violence, and the risk for mental illness among newly arrived refugees (NAR). The aim of this study is therefore to investigate the effect of pre-migration violent and threatening experiences on the mental health of NAR in Sweden. The participants were recruited between February 2015 and February 2016, undergoing the naturalisation process in Sweden.

Investigating pathways for predisposing, enabling and need factors in predicting the use of STI/HIV-testing services among Syrian and Iraqi migrants in Scania, Sweden - a cross-sectional study with directed acyclic graphs for modelling pathways to testing.

Background: Some groups of migrants have increased vulnerability to Sexually Transmitted Infections (STI) and Human Immunodeficiency Virus (HIV) transmission partly due to a lower uptake of disease preventive activities targeting the general population in receiving country. Limited access to economic and social resources and poor language skills may exacerbate exposure to sexual risks and utilization of health services.

Aim: To explore general and migrant specific predictors for STI/HIV-testing among Syrian and Iraqi migrants in Sweden and to investigate potential pathways that link predisposing, enabling and need- factors to STI/HIV-testing.

The hepatoprotective effect of aminoguanidine in acute liver injury caused by CCl in rats.

In this study, the hepatoprotective effect of aminoguanidine in acute liver damage caused by carbon tetrachloride-CCl at a dose of 1 mL/kg, i.p. was investigated in experimental rats.

Visual attention in change blindness for objects and shadows.

Studies have found that observers pay less attention to cast shadows in images than to better illuminated regions. In line with such observations, a recent study has suggested stronger change blindness for shadows than for objects (Ehinger et al., 2016).

Ambulance nurses' experiences of using prehospital guidelines for patients with acute chest pain - A qualitative study.

Background: Ambulance nurses have an important role in early recognition and treatment often being the first medical contact for patients with acute chest pain. However, there is sparse knowledge on the experiences of ambulance nurses with regard to use of Prehospital Guidelines for patients with Acute Chest Pain.

Aim: To explore ambulance nurses' experiences of using prehospital guidelines for patients with acute coronary syndrome.

Working With Refugees' Health During COVID-19-The Experience of Health- and Social Care Workers in Sweden.

Introduction: In Sweden, often seen as one of the most egalitarian countries, the COVID-19 pandemic exposed high levels of health inequality, especially harming people with a refugee background. This is also despite Sweden's image as a refugee-friendly country. In this context, the aim of this paper is to better understand how Swedish health- and social workers have reacted to the health- and social needs of refugees during the pandemic.

The Need for Parental Support for Migrant Parents in Transition Into Sweden: A Perspective.

Migration is a stressful experience and research shows that newly arrived migrants in Sweden suffer from different challenges and struggle to relate to parenting in a new culture that is different from their own. The Swedish Child Health Services (CHS) focuses on promoting health among children, as well as supporting parents in parenting. Although this is a goal, migrant parents participate at lower rates in parental support groups.

Do individual differences in face recognition ability moderate the other ethnicity effect?

Individuals are better at recognizing faces from their own ethnic group compared with other ethnicity faces-the (OEE). This finding is said to reflect differences in experience and familiarity to faces from other ethnicities relative to faces corresponding with the viewers' ethnicity. However, own-ethnicity face recognition performance ranges considerably within a population, from very poor to extremely good.

A Commentary on Several Study Design Considerations Pertaining to the Screening of Substances Extracted and/or Leached from Pharmaceutical Contact Materials.

The assessment of substances that can be extracted (extractables) or leached (leachables) from the materials that come in contact with pharmaceutical products often starts with a general screening of these substances in relevant samples. Although such screening studies may be of a qualitative and semi-quantitative nature, the data they generate are critical in ensuring the suitability of the system(s) used to manufacture, store, and/or administer the product. As such, it is important they are designed using appropriate analytical techniques and methodologies so that representative and reproducible data are obtained.

Risk for mental illness and family composition after migration to Sweden.

Objectives: The aim of the present study is to determine how marital status and certain post-migration family structures are associated with the risk of mental illness among recently arrived Arabic- speaking refugees in Sweden.

Methods: A cross-sectional study was conducted during 2015 and 2016. The study population was recruited by inviting all adult refugees who participated in the mandatory public integration support programme.

The Predation Game: Does dividing attention affect patterns of human foraging?

Attention is known to play an important role in shaping the behaviour of both human and animal foragers. Here, in three experiments, we built on previous interactive tasks to create an online foraging game for studying divided attention in human participants exposed to the (simulated) risk of predation. Participants used a "sheep" icon to collect items from different target categories randomly distributed across the display.