Rare Occurrence of Incidental Finding of Noninvasive Follicular Thyroid Neoplasm With Papillary-Like Nuclear Features in Hürthle Cell Adenoma.

Introduction: Hürthle cell adenoma is a rare benign lesion of the thyroid gland, however, controversies about its potential malignant behavior still remain. Among thyroid neoplasms, papillary carcinoma is the most common variant with great variety of histological subtypes demonstrating different biological behavior.

Aim: To raise the awareness of possible coexistence of these two lesions and discussion about possible therapeutic approaches.

Eccrine carcinoma in the foot of an Asian elephant (Elephas maximus).

A case of eccrine carcinoma of the interdigital foot glands in a 39-yr-old female Asian elephant (Elephas maximus) from Zagreb Zoo is described. The tumor between the toenails of the right forefoot was surgically removed 3 yr before postmortem examination (2003), and the histopathologic diagnosis was compound eccrine carcinoma characterized with glandular tubular and papillary proliferations, mild cellular pleomorphism, proliferation of the myoepithelial cells with mucoid secretions, and necrosis. Immunohistochemistry revealed strong immunoreactivity to S-100 protein, estrogen, and high-molecular weight cytokeratin.

Neuroendocrine tumors of larynx--two case reports and literature review.

Neuroendocrine tumors (NET) of the larynx are rare and heterogenous group, with much confusion about nature and classification of these neoplasms in the past. Diagnosis is based primarily on light microscopy and confirmed by immunohistochemistry and electron microscopy. A classification in 4 different types; paraganglioma, typical carcinoid, atypical carcinoid and small cell neuroendocrine carcinoma (SCNC) is a current consensus.

Thyroid metastasis from breast carcinoma resembling medullary thyroid carcinoma.

We are reporting a case of a 42-yr-old female with a history of right breast carcinoma. She was surgically treated (breast quadrantectomy with axillary dissection) and receiving a third cycle of adjuvant chemotherapy when a feeling of a constant pressure in the front of the neck and lack of air occurred. Subsequent work-up revealed a node in the right thyroid lobe with enlarged paratracheal bilateral and right mid and lower jugular lymph nodes.

[Locally invasive papillary thyroid cancer--our experience].

Differentiated thyroid carcinomas, particularly papillary carcinoma, are the tumors with good prognosis, but sometimes have a tendency to spread into the surrounding tissue. The spread of these tumors usually involves muscle, cartilage and upper aerodigestive tract. During two years (2008-2009) at the Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Center Zagreb, 233 patients with differentiated thyroid carcinoma were treated.

Orofacial granulomatosis treated with intralesional triamcinolone.

Orofacial granulomatosis (OFG) is an uncommon disease, usually presenting as recurrent or persistent swelling of the soft tissues in the orofacial region, predominantly lips (cheilitis granulomatosa). The cause of this illness is unknown. OFG may also be part of the triad of Melkersson-Rosenthal syndrome (MRS) and some consider it a monosymptomatic form of MRS.

Laryngeal inflammatory myofibroblastic tumor in a man: a case report.

Inflammatory myofibroblastic tumor (IMT) is a pseudosarcomatous lesion occurring in soft tissue and organs. It is known under a wide number of terms, such as inflammatory pseudotumor, plasma cell granuloma, pseudosarcomatous myofibroblastic proliferation. IMT is most commonly located in the lung, while laryngeal location is rarely described.

DNA ploidy in thymoma and associated multiple primary malignancies in the same patient.

Thymoma is an uncommon neoplasm derived from thymic epithelium. It is located in the anterosuperior mediastinum. Thymoma may be associated with different types of additional primary malignancies; however, colorectal adenocarcinoma and thyroid cancer appear to be most common.

Atypical lipoma: well-differentiated liposarcoma of the orbit with dedifferentiated areas.

Primary orbital liposarcoma is a very rare orbital tumor and dedifferentiation in the liposarcomas occurs rarely. Dedifferentiation is defined by development, in a well-differentiated tumor, of poorly differentiated, high-grade areas. The dedifferentiated liposarcomas (DDLS) have a better prognosis than pleomorphic sarcomas as a whole.