The bone microstructure from anterior cruciate ligament footprints is similar after ligament reconstruction and does not affect long-term outcomes.

Purpose: The purpose of this study was to assess the quality of the bone tissue microstructure from the footprints of the anterior cruciate ligament (ACL) and its impact on late follow-up outcomes in patients who undergo anterior cruciate ligament reconstruction (ACLR).

Methods: The records of 26 patients diagnosed with a completely torn ACL who underwent ACLR were collected. During the surgery performed using the Felmet method, bone blocks from the native ACL footprints were collected.

[Effect of cyclophosphamide on bone remodeling in rats].

Neoplasms, with or without metastases in bones, can induce pathological bone remodeling, leading to systemic bone resorption and hypercalcemia or osteomalacia and normocalcemia. The aim of the present study was to investigate the effect of a cytostatic--cyclophosphamide on the skeletal system in rats. The experiments were carried out in male Wistar rats with initial body weight of 212-229 g, divided into 3 groups (n = 6): I--Control, II--Cyclophosphamide (10 mg/kg m.