A new approach to the treatment of acute infection diseases with antibiotic-pectin formulae.

Introduction: Intestinal infections are a significant health issue; antibiotics are essential in treating acute intestinal infections. However, evidence in the literature shows that the excessive use of antibiotics has created many threats to human health. This work aimed to study the impact of apple pectin in combination with antibiotics on treating patients with amebiasis and dysentery.

Evaluation of Extended-release of Piroxicam-loaded Pectin-zein Hydrogel Microspheres: , , and Studies.

Objective: This study evaluated drug delivery systems based on Pectin (P) and Zein (Z) hydrogel microspheres. Piroxicam (Px) loaded P/Z hydrogel microspheres (P/Z HM) were developed, and their extended-release pharmacokinetic properties were evaluated.

Methods: Experiments were executed under three different conditions: in vitro, ex vivo, and in vivo.

Structural characterization of pectin obtained by different purification methods.

Commercial pectin production is based on vacuum evaporation and alcohol precipitation (VEAP) using large quantities of expensive and flammable alcohol. This process has high production costs that have greatly limited the commercial use of refined pectins. This study demonstrates a new technology using a diaultrafiltration (DUF) process in a pilot plant, which is a low-cost, green, and ecologically friendly way to produce pectin.

Chemical constituents of Ferula seravschanica.

Phytochemical investigation of Ferula seravschanica afforded seven new compounds, including three new bicyclic-type sesquiterpene coumarins (1-3), two new monocyclic-type sesquiterpene coumarins (16-17), two new phenylpropanoids (23-24) as well as twenty-two known compounds (4-15, 18-22, and 25-29). The structures of new compounds were determined by HRESIMS, NMR, ECD calculations, and X-ray single-crystal diffraction analysis. Furthermore, crude EtOAc extract and separated fractions (F1-F12) possessed cytotoxic activity against four human tumor cell lines (HT-29, DU145, HeLa, and Jurkat).

Fabrication, characterization and stability of oil in water nano-emulsions produced by apricot gum-pectin complexes.

In this study, the effects of apricot gum-apple pectin (AG/pectin) complex as an emulsifier and stabilizer on the sunflower oil in water nano-emulsion parameters including droplet size, zeta-potential, and the creaming index was investigated. The first independent variables were AG concentration in AG/pectin complex. Applying a 21.

Effect of ultrasonication, pH and heating on stability of apricot gum-lactoglobuline two layer nanoemulsions.

The objectives of this study were to evaluate the effect of apricot gum-lactoglobuline (AG/LgC) ratio, thermal treatment, sonication with different times and amplitudes and pH, on double layer sunflower oil in water emulsion stability. The emulsion stability was determined by the evaluation of emulsion performance indices including particle size, zeta potential, creaming and emulsion volume stability during 10 days of storage. Applying AG and LgC with the ratio of 12.

Novel modulation of drug delivery using binary zinc-alginate-pectinate polyspheres for zero-order kinetics over several days: experimental design strategy to elucidate the crosslinking mechanism.

A Box-Behnken design was applied to mathematically establish whether different degrees of crosslinking were induced by Zn2+ and Ca2+ ions in polyspheres composed of alginate and/or pectin, and the model drug ibuprofen. Based on their different crystal structures and coordination numbers, a theoretical model was proposed demonstrating that Zn2+ ions preferentially crosslink alginate and pectin. In addition, the lower coordination number of Zn2+ (4-6) would significantly retard hydration of both polymers, as opposed to Ca2+ (7-9).