Evaluation of the protective and therapeutic effects of gum aqueous extract on cellular and pathological aspects of experimental asthma in Balb/c mice.

Objective: The purpose of this study was to investigate the protective and therapeutic effects of aqueous extract of gum on an experimental asthma in BALB/c mice.

Materials And Methods: Aqueous extract of dried and milled gum was assemble and evaluate by GC-MS. In order to investigate the effect of gum extract on cellular and pathological aspects of asthma, 60 BALB/c mice were divided into six groups as: negative control, asthmatic group, asthmatic group receiving dexamethasone (1mg/kg; intraperitoneal (IP)) and three asthmatic groups receiving different concentrations of the extract (100, 200 and 400 mg/kg, orally) from the beginning of the study and continued for 84 days.