Publications by authors named "Zaya Makhbal"
Article Synopsis
- The study explored the genetic variants linked to sensorineural hearing impairment (SNHI) in Mongolian patients, who show different mutation patterns compared to other populations.
- Using next-generation sequencing on 99 patients, researchers found pathogenic variants in 54% of them, with a specific gene mutation being the most common.
- This research not only enhances knowledge of SNHI genetics in Mongolia but also emphasizes the need for tailored genetic testing and counseling based on population differences.
Genetic factors are an important cause of idiopathic sensorineural hearing impairment (SNHI). From the epidemiological perspective, mutations of three deafness genes: GJB2, SLC26A4, and MT-RNR1, are much more prevalent than those of other genes worldwide. However, mutation spectra of common deafness genes differ remarkably across different populations.
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