[The concept of ophthalmologic oncology development].

The authors review the research results concerning the diagnosis and treatment of ocular tumors over 25 years of activities of Department of Ophthalmooncology and Radiology and analyze the perspective trends for future studies.

[Metastatic involvement of liver in patients with uveal melanoma].

The efficacy of enucleation and brachitherapy is assessed in 1150 patients. The incidence of metastases is the highest (up to 2/3) occurs within the first 3 years. Neither enucleation, nor brachitherapy affect this value.

[Criteria for assessing the efficacy of brachytherapy of uveal melanomas, complications of therapy and there prevention].

The authors assess the efficacy of brachytherapy of uveal melanomas in 954 patients. Strontium ophthalmoapplicators were used in 652, rutenium ones in 302 patients. As a rule, Sr applicators were sutured in patients with tumors up to 3.

[Validation of the use of brachytherapy in uveal melanomas of juxtapapillary localization].

Forty-two patients with juxtacapillary melanomas of the choroid were treated by brachytherapy. The treatment was carried out in two stages: Stage I--separating laser coagulation, Stage II--irradiation with ophthalmologic applicators (90Sr, 90I). Complete resorption was achieved in 12 patients, partial regression with the process stabilization in 17, no effect in 13, in 11 of these enucleation had to be performed.

[Postradiation secondary glaucoma and prevention measures].

The authors have examined the possibility of preventing the development of secondary glaucoma after eye irradiation with a narrow medicinal proton beam. Twenty-eight patients with cilio-choroidal melanoma were involved in the study, 7 male and 21 female ones, aged 48.4 on an average.

[Experience in the treatment of eye tumors using a narrow medical proton beam].

This paper presents the effects of proton beam therapy of 175 patients with tumors of the eye. Irradiation was performed with a narrow medical proton beam (Institute of Theoretical and Experimental Physics) with the energy of 70 MeV (Bragg's peak). The total dose was 6000-7000 rad, irradiation frequency was 5-6 sessions every other day.

Ciliochoroidal melanomas treated with a narrow medical proton beam.

We treated 63 patients with intraocular melanomas by means of a narrow medical proton beam. Tumors were irradiated with 2,500 rad at each of four to five sessions, with an interval of one to two days between sessions. The melanomas ranged in diameter from 8 to 20 mm and were from 3.