Salivary pepsin A detection related to gastro-oesophageal reflux episodes in children undergoing impedance probe monitoring.

Aim: Gastro-oesophageal reflux is routinely diagnosed with invasive intraluminal impedance pH probe monitoring. This study aimed to determine whether gastric pepsin A detected in saliva of children correlates with gastro-oesophageal reflux.

Methods: Patients undergoing probe monitoring were prospectively recruited between 2014 and 2016 at a paediatric hospital.