Publications by authors named "Zanna J Voysey"
Article Synopsis
- Sleep dysfunction is common in Huntington's disease (HD) and can worsen symptoms and quality of life while potentially speeding up the disease's progression.
- Current treatments for HD do not address sleep issues or the effects of medications on sleep.
- The review evaluates existing research and presents a framework for understanding how different medications affect sleep, along with highlighting new therapies for sleep dysfunction in HD.
Sleep dysfunction is highly prevalent across the spectrum of neurodegenerative conditions and is a key determinant of quality of life for both patients and their families. Mounting recent evidence also suggests that such dysfunction exacerbates cognitive and affective clinical features of neurodegeneration, as well as disease progression through acceleration of pathogenic processes. Effective assessment and treatment of sleep dysfunction in neurodegeneration is therefore of paramount importance; yet robust therapeutic guidelines are lacking, owing in part to a historical paucity of effective treatments and trials.
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