Minoxidil and male-pattern alopecia: a potential role for a local regulator of sebum secretion with vasoconstrictive effects?

Regulation of the hair cycle takes place at the pilo-sebaceous unit with the sebaceous gland as a sex hormone-dependent part. Although minoxidil stimulates proliferation of follicular cells and activation of prostaglandin endoperoxide synthase-1, it was suggested that other mechanisms, such as an increase in the local blood flow, might mediate the drug effect on hair growth. If that is the case, it is possible that minoxidil counteracts some vasoconstrictive mediator of male-pattern alopecia.

[War injuries of the arteries].

The experience with military vascular injuries in the recent war in Crotia is reviewed. From April 1991 to October 1995, 197 wounded persons with 231 injuries of arteries were admitted to the University Hospital Rebro. The most common injuries were of lower extremity arteries (54.

Changes in vitamin E concentration after surgery and anesthesia.

Unlabelled: The aim of this randomized study was to examine changes in vitamin E concentration in female subjects (age 30-60, ASA I) after cholecystectomy and halothane (N = 16) or isoflurane (N = 16) anaesthesia. Vitamin E concentration was measured two days before, and then one, five and twenty-four hours and four days after surgery. High-pressure liquid chromatography was used for its determination.

[Sepsis in surgery patients].

The aim of the study was to determine therapeutic possibilities in surgical patients with sepsis following gunshot wounds of the abdomen and lower extremities. Thirty patients who underwent repeated surgical procedures in general or peridural anesthesia were analyzed. Eleven patients developed ARDS, of which 7 also had acute renal insufficiency and required hemodialysis.

[Epidural anesthesia in vascular surgery in patients with chronic obstructive lung disease].

Epidural anaesthesia was determined in 29 patients with chronic obstructive pulmonary disease. Lidocaine 2% for vascular procedures such as embolectomy from the arteriae femoralis and arteriae poplitea was used as an anesthetic in 12 patients and 0.5% bupivacaine for aortobitemoral or femoropopliteal bypass in 17 patients.

[The effect of propofol anesthesia with and without the use of opioid analgesia on cardiorespiratory stability in patients].

The possibility of use of propofol as an anesthetic induction agent was studied in 147 patients who were scheduled for trauma, abdominal, plastic and proctologic surgery. The patients were divided into 4 groups. Group I consisted of 39 patients who had anesthesia induced with propofol alone for outpatient operations.

[High colonic-vaginal fistulas].

In this paper, the authors present the definition, etiology, clinical features, diagnosis and preparations for the surgical treatment of colovaginal fistulas. A ten year experience with 11 female patients with colovaginal fistulas divided according to the causes is reviewed. The fistulas commonly resulted from the surgical treatment, radiotherapy, parturition injuries and Crohn's disease.

[Anesthesia in patients with varicose syndrome].

Pain in the muscles and the feeling of tension in the lower legs along the varicose veins brings many patients, especially women to an operation, usually after previous attempts of conservative treatment. The aim of the work was to present the choice of analgesia for the operation of the veins of the lower limbs with the control of the post-operative analgesia. The methods included two groups of patients.

[Anesthesiology problems in injuries of the retroperitoneum].

Patients with injured retroperitoneum present a great problem because of difficulties arising in their diagnosis and treatment. The aim of our work was to indicate the approach to such patients for the purpose of establishing the timely diagnostic and adequate treatment. The methods: Polytraumatized patients with retroperitoneal injuries were investigated, who during their treatment had the following complications: hemolysis, disseminated intravascular coagulation, and renal insufficiency.