Vonoprazan Fumarate: A Promising Therapeutic Option for the Rapid Relief of Laryngopharyngeal Reflux Disease.

Objective: The aim is to examine the Reflux Symptom Score-12 (RSS-12) and assess the effectiveness of vonoprazan fumarate in managing laryngopharyngeal reflux disease (LPRD) among the Chinese population.

Methods: A total of 140 patients with LPRD who were treated at our otorhinolaryngology outpatient clinic were included. The patients were randomly divided into the vonoprazan treatment group and the esomeprazole treatment group.

[The efficacy of vonoprazan fumarate in the treatment of laryngopharyngeal reflux disease evaluated by the Chinese version of the RSS-12 scale].

To explore the efficacy of vonoprazan fumarate in the treatment of laryngopharyngeal reflux disease（LPRD） evaluated by the Chinese version of the RSS-12 scale. A total of 100 LPRD patients treated in the otolaryngology-head and neck surgery outpatient clinic of our hospital were randomly divided into two groups（50 cases each）. The observation group was treated with vonoprazan fumarate（20 mg, once daily）, and the control group was treated with esomeprazole enteric-coated capsules（20 mg, twice daily） for 12 weeks.

The Shape of the Olfactory Bulb Predicts Olfactory Function.

The olfactory bulb (OB) plays a key role in the processing of olfactory information. A large body of research has shown that OB volumes correlate with olfactory function, which provides diagnostic and prognostic information in olfactory dysfunction. Still, the potential value of the OB shape remains unclear.

Brain response to odors presented inside the nose, directly in front of the nose or with ambient air.

Objective: Functional magnetic resonance imaging (fMRI) allows the measurement of changes in blood flow in association with changes in brain activity. This technique has been used frequently to study brain activation in response to odorous stimuli. The aim of this study was to evaluate the effects of odor delivery conditions on brain responses obtained with fMRI.

Apparently Minor Head Trauma Can Lead to Anosmia: A Case Report.

We report the case of a 49-year-old female patient who suffered from anosmia following an apparently mild head trauma when bumping into a door at her home. She reported no other accompanying symptoms after the injury that day. Olfactory function was completely lost, which was noted the day after the trauma.

Characteristics of Olfactory Disorder With and Without Reported Flavor Loss.

Objectives/hypothesis: Quality of life related to olfactory disorder (OD) depends on the perceived impairment. It is not known why some patients with OD report smell and flavor loss while others report smell loss only. In order to understand this, we compared the two clinical presentation forms in terms of demographics, clinical features, and orthonasal olfaction test results.

Individual variability of olfactory fMRI in normosmia and olfactory dysfunction.

Purpose: The diagnosis of olfactory dysfunction is mainly based on psychophysical measurements. The aim of the current study was to investigate how well the olfactory functional magnetic resonance imaging (fMRI) can effectively distinguish between normosmic people and subjects with olfactory dysfunction.

Methods: Thirty-eight participants were recruited for the study.

Is Handedness Associated with the Depth of the Olfactory Sulcus?

Background: Structural and functional asymmetry is frequent in biological systems. The aim of the present study was to examine whether there is a relation between handedness and the depth of the olfactory sulcus (OS) and reinvestigate whether there is a lateralization of OS depth.

Methods: Forty-two healthy volunteers (mean age 24.

Assessment of odor perception related to stimulation modes in a mock MRI scanner.

Background: Numerous studies investigated the central-nervous processing of olfactory information in humans, often based on functional MRI studies. However, when describing the olfactory perception, the course of olfactory sensations over time has received little attention although this constitutes a fundamental portion of the experimental paradigm. Hence, the aim of this study was to evaluate overall perception and the perception of odors over the time course of repeated odorous stimulation under different conditions of stimulus presentation.

Lateralization of odor identification in right-handers.

Odor identification is related to odor naming, which is more of a verbal than an olfactory sensory task. Linguistic functions in right-handers are typically lateralized to the left hemisphere of the brain and the olfactory processing happens predominantly ipsilaterally to the stimulated side. Re-investigate side-related effect in healthy right-handed people with a larger sample size and investigate the influence of age or gender on the odor identification lateralization effect.

Correction to: Magnetic Resonance Imaging of Human Olfactory Dysfunction.

The original version of this article unfortunately contained a mistake. The spelling of the Yoshi Akshita name was incorrect. The correct name should be Joshi Akshita The original article has been corrected.

Magnetic Resonance Imaging of Human Olfactory Dysfunction.

Olfactory dysfunctions affect a larger portion of population (up to 15% with partial olfactory loss, and 5% with complete olfactory loss) as compared to other sensory dysfunctions (e.g. auditory or visual) and have a negative impact on the life quality.

Short or long runs: An exploratory study of odor-induced fMRI design.

Objective: Functional magnetic resonance imaging (fMRI) is a non-invasive neuroimaging technique widely used in olfactory research. During a typical fMRI olfactory block-design, one functional "run" refers to a combination of multiple blocks with continuous brain image acquisition. The current study investigated the length of functional runs on odor-induced brain response signals (blood oxygen level dependent [BLOD]) within the primary and key secondary olfactory areas.

Quality of Life in Patients With Olfactory Loss Is Better Predicted by Flavor Identification Than by Orthonasal Olfactory Function.

To date, most studies on the relationship between chemosensory performance and quality of life have focused on orthonasal measures of olfactory function. In the current investigation, we examined the predictive value of orthonasal and flavor identification indices of olfactory function on a wide spectrum of health and sociopsychological factors, including quality of life, life satisfaction, overall health, and depressive symptoms. Participants were 178 ENT patients (Mage = 58 ± 1), representing various causes of olfactory loss: idiopathic smell loss (n = 51; Mage = 63 ± 2), sinunasal disease (n = 27; Mage = 56 ± 3), head trauma (n = 33; Mage = 51 ± 2), and infections of the upper respiratory tract (n = 67; Mage = 59 ± 2).

[Blood supply of the pedicle nasal septum mucosa flap of rabbit in experiment].

Objective: To explore the blood supply of the pedicle nasal septum mucosa flap of rabbit, in order to supply the theory and experiment basis for making the pedicle nasal septum mucosa flap to repair nasal cavity and skull base defect.

Method: Twenty rabbits corpses were induced into the experimental subject, and inject 5 ml blue ink into the external carotid artery, then longitudinal cut apart the middle head of rabbit, finally observe the blood supply of the pedicle nasal septum mucosa flap.

Result: The blood supply of the pedicle nasal septum mucosa flap mostly come from the vessels of extremitas anterior part of nasal septum.