Publications by authors named "Zan Yang Shi"
Background: To investigate the relationship between the OPRM1 gene A118G polymorphism and intracranial hemorrhage (ICH) in premature infants and identify the relevant genes in disease occurrence.
Methods: In the present case study analysis, polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was used to detect the genotype and allele frequencies of the OPRM1 gene All8G single nucleotide polymorphism (SNP) in a case group of premature infants with ICH (n=167) and a control group of premature infants (n=163) without ICH.
Results: In the case group, 73 (43.
Article Synopsis
- This study assesses NT-proBNP levels alongside spontaneous breathing trials to predict ventilator weaning success in preterm infants with respiratory distress syndrome (RDS).
- Out of 88 infants, 63 passed the breathing trials, but 16 were later reintubated, indicating weaning failure, which was linked to lower gestational age and higher NT-proBNP levels.
- The research concludes that NT-proBNP is a reliable predictor of weaning failure, suggesting its measurement before trials could enhance weaning outcomes.
Article Synopsis
- The study investigates the link between Val279Phe SNPs in the PAF-AH gene and intracranial hemorrhage in preterm infants.
- A case-control design compared 58 preterm infants with hemorrhage and 65 without, using PCR to analyze genetic variations.
- Results showed significant differences in genotype and allele frequencies between groups, suggesting that specific SNPs may increase the risk of intracranial hemorrhage.