Publications by authors named "Zameer Aziz"
Article Synopsis
- This updated meta-analysis examines the effectiveness and safety of the SENTINEL Cerebral Protection System during transcatheter aortic valve implantation (TAVI), revealing mixed results across various studies.
- The analysis included 15 studies with over 294,000 patients, finding significant reductions in mortality and strokes (both all and disabling) when using the SENTINEL device, especially in studies focusing on outcomes within 30 days.
- Despite positive findings, there was notable variability in outcome results, particularly for mortality and overall stroke rates among the studies, indicating a need for further research to clarify these differences.
Article Synopsis
- The study examines outcomes of three aortic valve replacement (AVR) techniques: transcatheter (TAVI), minimally invasive (MIAVR), and conventional (CAVR), focusing on all-cause mortality rates.
- A total of 27 studies with over 16,000 patients were analyzed, revealing that TAVI initially had lower mortality compared to CAVR, but this advantage diminished after 37.5 months.
- MIAVR demonstrated significantly lower mortality rates than both TAVI and CAVR, although TAVI showed consistent benefits specifically in patients undergoing transfemoral (TF) procedures; however, more research is needed for conclusive results.
Introduction: Data on patients with small aortic annuli (SAA) undergoing transcatheter aortic valve implantation (TAVI) are limited. We aim to describe the impact of aortic annular size, particularly SAA and TAVI valve type on valve haemodynamics, durability and clinical outcomes.
Method: All patients in National Heart Centre Singapore who underwent transfemoral TAVI for severe symptomatic native aortic stenosis from July 2012 to December 2019 were included.
The objective of this study was to evaluate the epidemiology of diabetic foot infections (DFIs) and its predictive factors for lower extremity amputations. A prospective study of 100 patients with DFIs treated at the National University Hospital of Singapore were recruited in the study during the period of January 2005-June 2005. A protocol was designed to document patient's demographics, type of DFI, presence of neuropathy and/or vasculopathy and its final outcome.
View Article and Find Full Text PDFOur aim of this study was to compare the accuracy of three different modalities for testing sensory neuropathy in diabetic patients with and without diabetic foot problems. The three devices used included the pin-prick testing using the Neurotip® (PPT), the Semmes-Weinstein 5.07/10 g monofilament testing (SWMT), and the rapid-current perception threshold (R-CPT) measurements using the Neurometer® testing.
View Article and Find Full Text PDFIntroduction: This study aims to evaluate the results of foot screening performed in a study population of 2137 diabetics (3926 feet) screened from 2006 to 2008 by the National University Hospital (NUH) multi-disciplinary team for diabetic foot problems.
Materials And Methods: A standardised protocol was designed. Foot screening consisted of detailed history taking and clinical examination including assessment for sensory neuropathy by Semmes Weinstein monofilament (SWMF) and neurothesiometer and assessment of vasculopathy by ankle-brachial index (ABI) and total body irradiation (TBI).