Estimation of effective dose and risk of exposure-induced cancer death, and diagnostic reference level for CT scans in Tabriz, Iran.

This study aimed to estimate the effective dose and the risk of exposure-induced cancer death (REID), as well as to establish diagnostic reference levels (DRLs) for common CT examinations conducted in Tabriz, Iran. The investigation included adult patients undergoing abdomen-pelvis, brain, neck, sinus, and chest CT scans. Patient data, exposure parameters, and radiation dose metrics, such as volume CT dose index (CTDI) and dose length product (DLP), were collected and analyzed.

Zinc oxide fabricated by rutin as potent anti-leukemia nanostructure.

Treatment of chronic myeloid leukemia (CML) is a significant therapeutic challenge, and exploration of novel treatment approaches is an urgent necessity. This work investigates the anticancer properties of rutin-conjugated zinc oxide nanoparticles (Rut-ZnO NPs) against CML cells. Physicochemical properties of the NPs were studied by FT-IR, FE-SEM, XRD, zeta potential, and DLS analyses.

ZnO-Rutin nanostructure as a potent antibiofilm agent against Pseudomonasaeruginosa.

Pseudomonas aeruginosa is a common human pathogen that is resistant to multiple antibiotics due to its ability to form biofilms. Developing novel nanoformulations capable of inhibiting and removing biofilms offers a promising solution for controlling biofilm-related infections. In this study, we investigated the anti-biofilm activity of rutin-conjugated ZnO nanoparticles (ZnO-Rutin NPs) in pathogenic strains of P.

Buspirone administration: Influence on growth, spawning, immune response, and stress in female goldfish ().

The current study evaluated the impact of buspirone supplementation on the growth, physiology, stress response, spawning, and immunity in female goldfish (). For this purpose, buspirone was dissolved in absolute methanol and sprayed onto the feed to create four experimental groups: B0 (control), B25 (25 mg kg), B50 (50 mg kg), and B100 (100 mg kg). Fish were fed their respective diets for 56 days and subjected to stress using the air exposure method at the end of the experiment.

A Case Report of Thoracic Ectopia Cordis in a Hospital in Zanjan, Iran.

Methods: A 17-week-old female neonate with a history of prenatal diagnosis of congenital heart anomaly was admitted to Ayatollah Mousavi Hospital in Zanjan, Iran. For the diagnosis of thoracic ectopia, cordis fetal echocardiography and ultrasonography were performed. Moreover, the noninvasive prenatal testing (NIPT) genetic test performed in the 10th week of pregnancy was evaluated.

Curcumin Aattenuates the Expression of Metalloprotease (AHA_0978) and Serine Protease (AHA_3857) Genes in Aeromonas Hydrophila.

Background: Aeromonas hydrophila is a pathogenic bacterium responsible for various infections in humans and animals. Bacterial exoproteases are considered an important determinant in the pathogenicity of A. hydrophila.

Fetal Strain and Strain Rate Measured with Speckle Tracking Echocardiography in Maternal Diabetes: Systematic Review.

Introduction: The aim of this systematic review and meta-analysis was to evaluate fetal cardiac function in fetuses of mothers with diabetes compared to those of mothers without diabetes using 2D-STE.

Methods: Embase, MEDLINE, and CENTRAL were searched for observational studies on 2D-STE fetal left and right ventricular global longitudinal strain and strain rate that included singleton, non-anomalous pregnancies complicated by pregestational or gestational diabetes mellitus compared to uncomplicated pregnancies. The strain values were pooled per 4 weeks of gestation for meta-analysis using random-effects models.

An update on the molecular mechanisms of ZFAS1 as a prognostic, diagnostic, or therapeutic biomarker in cancers.

Zinc finger antisense 1 (ZFAS1), a newly discovered long noncoding RNA, is expressed in various tissues and organs and has been introduced an oncogenic gene in human malignancies. In various cancers, ZFAS1 regulates apoptosis, cell proliferation, the cell cycle, migration, translation, rRNA processing, and spliceosomal snRNP assembly; targets signaling cascades; and interacts with transcription factors via binding to key proteins and miRNAs, with conflicting findings on its effect on these processes. ZFAS1 is elevated in different types of cancer, like colorectal, colon, osteosarcoma, and gastric cancer.

Radiation doses and diagnostic reference levels for common CT scans in adults in Northwest region of Iran.

This study aims to estimate organ dose and cancer risks, establish region-specific diagnostic reference levels (DRLs), and determine achievable doses (ADs) for common CT procedures in adults in the northwest of Iran. Effective and organ doses were estimated using VirtualDoseCT software in a sample of 480 adult patients who underwent head, sinus, chest, and abdomen-pelvis (AP) CT scans. The guidelines provided by the BEIR VII report were utilized to estimate cancer risks.

Rutin-coated zinc oxide nanoparticles: a promising antivirulence formulation against pathogenic bacteria.

The use of engineered nanoparticles against pathogenic bacteria has gained attention. In this study, zinc oxide nanoparticles conjugated with rutin were synthesized and their antivirulence properties against Pseudomonas aeruginosa and Staphylococcus aureus. The physicochemical characteristics of ZnO-Rutin NPs were investigated using SEM, FT-IR, XRD, DLS, EDS, and zeta potential analyses.

From a bimodal to a multi-stage view on trypanosomes' differential RNA editing.

Significant variations in the abundance of mitochondrial RNA processing proteins and their target RNAs across trypanosome life stages present an opportunity to explore the regulatory mechanisms that drive these changes. Utilizing omics approaches can uncover unconventional targets, aiding our understanding of the parasites' adaptation and enabling targeted interventions for differentiation.

Inguinal endometriosis: a case series and review of the literature.

Background: Inguinal endometriosis is one of the most common forms of endometriosis. The present study introduces 8 cases of inguinal endometriosis and discusses probable theories of inguinal endometriosis by reviewing the literature.

Case Presentation: 8 Iranian cases of inguinal endometriosis with a mean age of 36 years were presented.

Diclofenac-loaded PLGA nanoparticles downregulate LasI/R quorum sensing genes in pathogenic P. aeruginosa isolates.

Poly(lactic-co-glycolic acid) (PLGA) is a biocompatible polymer that can gradually and consistently release drugs in a controlled manner. In this study, diclofenac sodium-loaded PLGA nanoparticles (DS-PLGA NPs) were produced by solvent evaporation technique and characterized using SEM, DLS, and zeta potential analyses. The antibacterial and antivirulence potential of DS-PLGA NPs against P.

Interaction of FeO nanoparticles with marine microalga Chlorella sorokiniana: Analysis of growth, morphological changes and biochemical composition.

The wide utilization of iron-based nanoparticles (NPs) based on their preferential properties has led to the discharge and accumulation of these materials into the aquatic environment. In this regard, a comparative study of different concentrations of α-FeO NPs and their micro form was conducted using microalga Chlorella sorokiniana up to the stationary growth phase. This study revealed that high concentrations of NPs (100 and 200 mg L) imposed a stressful condition on algal cells documented by a reduction in microalga growth, including cell number and specific growth rate.

Aortic Pseudoaneurysm following Ventricular Septal Defect Closure in a Pediatric Patient: A Case Report and Literature Review.

Aortic pseudoaneurysm, a rare condition characterized by localized transmural disruption and dilatation of the aorta, is very rare in the pediatric population. It is primarily caused by previous cardiovascular procedures such as aortic coarctation repair, aortic valve replacement, and subaortic membrane resection. We present a unique case of aortic pseudoaneurysm following surgery to repair a perimembranous ventricular septal defect in a 19-month-old boy who presented with fever as the sole symptom.

Beneficial effects of the combination of BCc1 and Hep-S nanochelating-based medicines on IL-6 in hospitalized moderate COVID-19 adult patients: a randomized, double-blind, placebo-controlled clinical trial.

Background: In the severe forms of COVID-19 and many other infectious diseases, the patients develop a cytokine storm syndrome (CSS) where pro-inflammatory cytokines such as IL-6 and TNF-α play a key role in the development of this serious process. Selenium and iron are two important trace minerals, and their metabolism is tightly connected to immune system function. Numerous studies highlight the role of selenium and iron metabolism changes in the procedure of COVID-19 inflammation.

In vitro and in silico assessment of anti-quorum sensing activity of Naproxen against Pseudomonas aeruginosa.

Serious infections caused by Pseudomonas aeruginosa are usually related to quorum sensing (QS)-dependent virulence factors. Hence, QS inhibition is a promising approach to overcoming P. aeruginosa infections.

A Systematic Review of the Whale Optimization Algorithm: Theoretical Foundation, Improvements, and Hybridizations.

Despite the simplicity of the whale optimization algorithm (WOA) and its success in solving some optimization problems, it faces many issues. Thus, WOA has attracted scholars' attention, and researchers frequently prefer to employ and improve it to address real-world application optimization problems. As a result, many WOA variations have been developed, usually using two main approaches improvement and hybridization.

Antibacterial potential and cytotoxic activity of iron oxide nanoparticles conjugated with thymol (FeO@Glu-Thymol) on breast cancer cells and investigating the expression of BAX, CASP8, and BCL-2 genes.

The use of metal nanoparticles (NPs) conjugated with natural herbal molecules in biomedical applications has been growing. In this work, we synthesized Iron oxide NPs conjugated with thymol (FeO@Glu-Thymol) and investigated their antibacterial and anticancer potentials. Physicochemical features of the NPs were studied by FT-IR, EDS-mapping, XRD, DLS, zeta potential, and electron microscopy.

Fixed-time sliding-mode distributed consensus and formation control of disturbed fractional-order multi-agent systems.

In this paper, fixed-time consensus and formation control for fractional-order multi-agent systems with a dynamic virtual leader in the presence of external disturbances is investigated. Consensus is achieved in fixed-time, i.e.

MMKE: Multi-trial vector-based monkey king evolution algorithm and its applications for engineering optimization problems.

Monkey king evolution (MKE) is a population-based differential evolutionary algorithm in which the single evolution strategy and the control parameter affect the convergence and the balance between exploration and exploitation. Since evolution strategies have a considerable impact on the performance of algorithms, collaborating multiple strategies can significantly enhance the abilities of algorithms. This is our motivation to propose a multi-trial vector-based monkey king evolution algorithm named MMKE.

Boosting bone cell growth using nanofibrous carboxymethylated cellulose and chitosan on titanium dioxide nanotube array with dual surface charges as a novel multifunctional bioimplant surface.

One of the most vital aspects of the orthopedic implant field has been the development of multifunctional coatings that improve bone-implant contact while simultaneously preventing bacterial infection. The present study investigates the fabrication and characterization of multifunctional polysaccharides, including carboxymethyl cellulose (CMCn) and carboxymethyl chitosan nanofibers (CMCHn), as a novel implant coating on titania nanotube arrays (T). Field emission scanning electron microscopy (FESEM) images revealed a nanofibrous morphology with a narrow diameter for CMCn and CMCHn, similar to extracellular matrix nanostructures.

Synthesis and comparison of three photocatalysts for degrading tramadol as an analgesic and widely used drug in water samples.

Tramadol is an analgesic drug that is mainly excreted in the urine. The entry of Tramadol into water samples causes their biological contamination. Therefore, three catalysts such as bismuth ferrite, cobalt-doped bismuth ferrite, and a magnetized Keggin type of polyoxometalate (α-FeO@phosphotungstic acid), were synthesized as photocatalysts to degrade Tramadol in water samples.

Powerful and fast nanostructure electrochemical sensor for monitoring of carbidopa catechol-based drug in water and biological fluids.

Herein, to monitor the concentration of carbidopa in an aqueous solution, an analytical approach based on electrode surface modification by Pt/SWCNTs as a sensor has been proposed. Pt/SWCNTs was synthesized by polyol strategy and characterized by the TEM method. Results confirmed spherical Pt nanoparticles with a diameter of about 10 nm decorated at the surface of SWCNTs with good distribution.

Effects of External Focus and Motor Control Training in Comparison with Motor Control Training Alone on Pain, Thickness of Trunk Muscles and Function of Patients with Recurrent Low Back Pain: A Single Blinded, Randomized Controlled Trial.

Background: Recurrent low back pain (RLBP) affects different structures in the lumbar spine. Exercise therapy is highly recommended as one of the first-line treatments. One crucial variable introduced to enhance RLBP is the external focus.