Publications by authors named "Zaman Sheikh"
Article Synopsis
- - Jamaican children are exposed to mercury (Hg) primarily through their diet, particularly from consuming saltwater and canned fish, which can negatively affect neurodevelopment.
- - The study examined the relationship between environmental Hg exposure, specific GST genes (GSTT1, GSTM1, GSTP1), and blood mercury concentrations in a sample of 375 children aged 2-8.
- - Results showed that the impact of consuming canned fish on blood Hg levels is stronger in children with specific GSTP1 genotypes, emphasizing the need for further research in other populations.
Article Synopsis
- * A study involving 375 children in Jamaica examined how environmental and sociodemographic factors affect blood arsenic levels, revealing significant links to factors like age and parental education.
- * Children with a specific GST gene variant (Ile/Ile) were found to have increased odds of elevated blood arsenic levels if they consumed avocados, highlighting the interaction between genetics and diet.
: To assess the safety and reactogenicity of single oral dose of heat-stable rotavirus vaccine (HSRV) in healthy adults aged 18-45 years followed by assessment of safety, reactogenicity, and immunogenicity of three doses of HSRV in healthy infants aged 6-8 weeks at enrollment.: Single-center randomized controlled, sequential, blinded (adults) and open-label (infants).: Single site at International Center for Diarrheal Disease Research, Bangladesh (icddr,b).
View Article and Find Full Text PDFPattern Of Dyslipidaemia And Its Association With Hypovitaminosis D In Type 2 Diabetes Mellitus.
J Ayub Med Coll Abbottabad
July 2018
Background: Macrovascular atherosclerosis is an important long-term complication of type 2 diabetes mellitus. Concurrent dyslipidaemia acts as an additional risk factor for these complications. Hypovitaminosis D has been associated with adverse cardiovascular events.
View Article and Find Full Text PDFBackground: To support vaccination programs in developing countries, a 4-dose vial presentation of pneumococcal non-typeable Haemophilus influenzae protein D-conjugate vaccine (PHiD-CV) was developed. This study assessed immunologic non-inferiority and safety of the investigational PHiD-CV 4-dose versus licensed 1-dose vial presentation in infants.
Methods: In this phase III, mono-center, observer-blind study in Bangladesh, 6-10-week-old infants were randomized 1:1 to receive PHiD-CV primary vaccination (at ages 6, 10, 18 weeks) and a booster dose (at age 9 months) with a 4-dose vial (with preservative, 4DV group) or 1-dose vial (preservative-free, 1DV group).