Publications by authors named "Zalaudek Iris"
Riehl's melanosis (RM) is a pigmentary disorder, more common in individuals with dark skin phototypes, considered a form of pigmented contact dermatitis. In this paper we present a case of RM due to the rubber component of a work facial mask in which dermoscopy and patch test were the most important tools to help physicians in diagnosis. In addition, we reviewed the main dermoscopic clues that may be useful in differential diagnosis with other facial pigmentary disorders.
View Article and Find Full Text PDFSporadic hidradenitis suppurativa (spHS) is a multifactorial disease in which genetic predisposition is intertwined with environmental factors. Owing to the still-to-date limited knowledge of spHS genetics, we calculated polygenic scores (PGSs) to study the genetic underpinnings that contribute to spHS within European demographic. A total of 256 patients with spHS and 1686 healthy controls were analyzed across 6 European clinical centers.
View Article and Find Full Text PDFIntroduction: Ultraviolet-based dermoscopy may support the recognition of scabies, yet neither accuracy analyses nor data on skin of colour are available. The aim of this multicentric observational retrospective was to investigate the diagnostic accuracy of polarised and ultraviolet-induced fluorescence (UVF) dermoscopic examination in both fair and dark skin, also assessing possible differences according to the skin tone.
Methods: Consecutive patients with a diagnosis of scabies were eligible.
A unique collaboration of multi-disciplinary experts from the European Association of Dermato-Oncology (EADO), the European Dermatology Forum (EDF), and the European Organization of Research and Treatment of Cancer (EORTC) was formed to make recommendations on cutaneous melanoma diagnosis and treatment, based on systematic literature reviews and the experts' experience. Cutaneous melanomas are excised with one to two-centimeter safety margins. For a correct stage classification and treatment decision, a sentinel lymph node biopsy shall be offered in patients with tumor thickness ≥ 1.
View Article and Find Full Text PDFThis guideline was developed in close collaboration with multidisciplinary experts from the European Association of Dermato-Oncology (EADO), the European Dermatology Forum (EDF) and the European Organization for Research and Treatment of Cancer (EORTC). Recommendations for the diagnosis and treatment of melanoma were developed on the basis of systematic literature research and consensus conferences. Cutaneous melanoma (CM) is the most dangerous form of skin tumor and accounts for 90 % of skin cancer mortality.
View Article and Find Full Text PDFBackground: Some people may compulsively desire to suntan despite the negative consequences, exhibiting symptoms similar to addictive disorders. Tanning dependence (TD) should be considered a risk factor leading to excessive sunbathing and thus increasing the risk of skin cancers. The aim of the present study was to investigate the tanning habits of the inhabitants of Trieste, a Northeastern Italian town characterized by high melanoma incidence.
View Article and Find Full Text PDFArticle Synopsis
- This study compares CO2 laser treatment and surgical deroofing for managing hidradenitis suppurativa (HS) tunnels, focusing on the effectiveness of each method in terms of healing time, pain, and cosmetic results.
- The results showed that the CO2 laser group had a significantly shorter healing time and lower pain perception compared to the surgical deroofing group, with mean healing times of 4.7 weeks versus 10.9 weeks.
- Both treatments had low complication rates and similar rates of complete healing at a 6-month follow-up, indicating that while CO2 laser might offer quicker recovery, both methods are effective for HS tunnels.
Article Synopsis
- Diagnosing atypical pigmented facial lesions (aPFLs) is difficult for dermatologists and crucial for patient care, as incorrect diagnoses can lead to mismanagement and delays in treatment.
- The study compared machine learning and deep learning models to improve diagnostic accuracy of aPFLs using 1197 dermoscopic images classified into seven categories, focusing on the potential role of AI in supporting clinicians.
- Results showed that while dermatologists were 71.2% accurate in identifying malignant versus benign lesions, their accuracy dropped to 42.9% when distinguishing among specific lesions, highlighting the complexity of aPFL evaluations.
Article Synopsis
- Diagnosing acral melanocytic lesions, like acral nevi and melanoma, can be difficult, and the BRAAFF checklist was developed to assist in this process but hasn't been validated yet.
- In a study, varying experts diagnosed images of nevi and melanomas using the BRAAFF checklist online, yielding a sensitivity of 92.5% and a specificity of 65.0%, comparable to traditional pattern recognition.
- The checklist showed varying levels of agreement among raters based on experience, and a simplified version achieved similar sensitivity with slightly lower specificity, suggesting that the BRAAFF checklist is a helpful but not superior diagnostic tool.
Article Synopsis
- Diagnosing solitary pink skin lesions is challenging due to the overlap of clinical features among both benign (like cherry angiomas) and malignant lesions (such as basal cell carcinoma).
- Reflectance confocal microscopy (RCM) improves diagnostic accuracy beyond traditional dermoscopy, offering better sensitivity and specificity for identifying these lesions.
- Despite advancements, a definitive diagnosis still requires surgical excision and histopathological analysis to ensure correct treatment.
Dermatophytosis is a prevalent superficial infection caused by filamentous fungi, primarily affecting the skin and/or its appendages. In recent years, there has been a notable increase in mycotic strains resistant to standard antifungal therapies, including , a dermatophyte of the complex. This review aims to provide a comprehensive overview of the treatment options for , elucidating their effectiveness in managing this challenging mycotic infection.
View Article and Find Full Text PDFBackground: Alopecia areata (AA) is an organ-specific autoimmune disease that affects the hair follicles of the scalp and the rest of the body causing hair loss. Due to the unpredictable course of AA and the different degrees of severity of hair loss, only a few well-designed clinical studies with a low number of patients are available. Also, there is no specific cure, but topical and systemic anti-inflammatory and immune system suppressant drugs are used for treatment.
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- Skin cancers are super common, especially in people with fair skin, and most of them are caused by UV rays from the sun, which means we can do things to prevent them.
- Experts from different continents suggest that fair-skinned people, especially kids, should stay out of the sun when the UV level is 3 or higher and use protection like hats, sunglasses, clothing, and sunscreen.
- They also believe sunbathing and using tanning beds are unhealthy, so they want to spread these ideas to help everyone stay safe from skin cancer.
Dermoscopy to differentiate clinically similar inflammatory and neoplastic skin lesions.
Ital J Dermatol Venerol
April 2024
Article Synopsis
- - Dermoscopy is a valuable imaging technique for dermatologists that helps distinguish between neoplastic (tumor-related) and inflammatory skin conditions, especially in tricky cases where they may appear similar.
- - A review of literature identified key dermoscopic features that can aid in differentiating 12 common challenging skin scenarios, such as distinguishing between Bowen's disease and psoriasis.
- - The study concludes that dermoscopy can significantly assist in differentiating between clinically similar skin lesions, improving diagnosis and treatment strategies.
Article Synopsis
- The study focused on the characteristics and dermatoscopic features of cutaneous metastases (CMs) from various primary tumors, highlighting the challenge of diagnosing them.
- A total of 583 patients were analyzed, with melanomas being the most common primary tumors, and a significant portion of the metastases was found in the head and neck region.
- The findings suggest that pigmented melanoma metastases often appear as structureless blue lesions, while amelanotic metastases display linear serpentine vessels; both types can be confused with other skin lesions.