Tumorlike eosinophilic granuloma of the skin.

In 1952, Kuske reported on a patient with a peculiar tumor on the dorsum of the right hand; histological analysis revealed a dense dermal infiltrate with numerous eosinophils. Not aware of any similar case report in the literature, he coined the descriptive term "tumor-like eosinophilic granuloma of the skin." In 1995, a 55-year-old white man with cancer of the prostate presented with a 4-month history of two reddish-brown, solid skin tumors on his left forearm and on the right side of his abdomen, respectively.

T cell involvement in persulfate triggered occupational contact dermatitis and asthma.

Background: Ammonium and potassium persulfates may induce a variety of cutaneous and respiratory diseases. The precise underlying mechanisms, however, are unclear.

Objective: To describe a hairdresser, who developed contact dermatitis, rhinoconjuntivitis, and bronchial asthma of delayed onset after occupational exposure to hair bleaches containing persulfate salts and to provide evidence for a common T-cell mediated mechanism responsible for the clinical manifestations.

[Erythema elevatum diutinum. A rare dermatosis with a broad spectrum of associated illnesses].

Erythema elevatum diutinum (EED) is a rare disease presenting with persistent red to yellow-brown papules or plaques which are mainly localized symmetrically on the extensor aspects of the hands and fingers, the elbows and the knees. The histology shows a leucocytoclastic vasculitis in early lesions and fibrosis of the dermis later on. Dapsone is the treatment of choice.

Kaposi's sarcoma as manifestation of immunosuppression in organ transplant recipients.

We report 2 patients, negative for human immunodeficiency virus (HIV) antibodies, who developed generalized Kaposi's sarcoma (KS), one 5 months after renal transplantation while receiving cyclosporin A and prednisone, and the other 24 months after heart transplantation while receiving cyclosporin A, azathioprine and prednisone. Reduction of the immunosuppressive therapy combined with chemotherapy and radiotherapy in both cases led to a remission of KS without development of transplant rejection.

Malignant atrophic papulosis.

We describe a 34-year-old woman presenting with a 1-year history of asymptomatic, atrophic papules disseminated mainly on the trunk. The clinical features were characteristic of malignant atrophic papulosis, and the histopathologic features were confirmatory. The etiology of this rare condition, described for the first time in 1941, remains unknown.

[Angioma serpiginosum, a skin change along Blaschko lines?].

We present a 34-year-old woman with angioma serpiginosum on the medial aspect of the left thigh, extending to the groin and the lower abdomen, and on the volar aspect of the left forearm. In addition to the late onset, the distribution along the lines of Blaschko was a remarkable feature of this case. We therefore reexamined our recent cases of angioma serpiginosum.

Livedo racemosa: a report of five cases.

We present 5 patients in whom the diagnosis of livedo racemosa gave rise to clinical and laboratory investigations revealing arterial disease of different etiologies. This presentation emphasizes the importance of not missing the clinical diagnosis of livedo racemosa.

Chronic cutaneous infection caused by Mycobacterium gordonae.

We report on a patient with a chronic nodular cutaneous infection histologically presenting with tuberculoid granulomas and growing Mycobacterium gordonae in culture from a biopsy. The lesions were treated surgically. M.

Pigmentation following long-term bismuth therapy for pneumatosis cystoides intestinalis.

In the recent literature, only a few reports deal with generalized pigmentation caused by bismuth treatment. We report a patient developing generalized pigmentation of the skin and mucous membranes without further signs of chronic bismuth poisoning following long-term administration of bismuth for pneumatosis cystoides intestinalis. Bismuth deposits were documented in a skin biopsy.

[Eccrine angiomatous nevus].

A case of eccrine angiomatous nevus in a 46-year-old woman is described. The histological examination revealed convolutions of eccrine sweat glands with no major structural abnormalities, and a closely related angiomatous component. Two components of this tumour are of special interest: the bone formation and a medium-sized artery with pathologic wall structure.

[Sneddon syndrome].

A 44-year-old female with Sneddon's syndrome, i.e. generalized racemose livedo and recurrent cerebrovascular disease, is presented.

[Extensive acrodermatitis chronica atrophicans involving the face].

We report on an 81-year-old woman suffering from extensive acrodermatitis chronica atrophicans with facial involvement. This unusual manifestation may be related to an immunodeficiency state in the course of multiple malignancies. The cutaneous lesions cleared significantly during an aminopenicillin therapy administered orally over 4 weeks.

[Roentgen ray-induced pemphigus vulgaris].

The pemphigus vulgaris lesions first developed in a 70-year-old man as a reaction to superficial X-ray treatment of solar keratoses on the forehead.

Metastatic eccrine sweat gland carcinoma: case report.

Eccrine sweat gland carcinoma is a rare malignancy of skin adnexa with potential aggressive growth and metastatic spread. We report here a case of eccrine carcinoma arising on a finger with widespread pulmonary metastasis. A brief synopsis of the pathological and clinical aspects of eccrine sweat gland carcinoma is presented and currently available therapeutic modalities are discussed.

[Removal of tattoos with the Nd:YAG laser].

Irradiation of 20 tattoos using the Q-switched Nd:YAG laser (energy density 3-5 J/cm2, asymmetrical pulse shape with 50% energy output in 18 ns, spot size 3 mm in diameter) gave the impression that black ink tattoos can be completely removed without scarring. Some patients needed several treatments. The results continued to improve even some months after the irradiation.

[Green lacewing larvae (Chrysopidae) as accidental ectoparasites of the human].

The larvae of green lacewings (Chrysopidae) may occasionally attack man as temporary ectoparasites, causing papular reactions similar to those produced by gnat bites.

[Acquired cutis laxa (elastolysis generalisata)].

Following glomerulonephritis with subsequent anasarca and repeated penicillin treatments, generalized cutis laxa developed in a forty-year-old patient. Progressive signs of pulmonary emphysema appeared in the same period. Additionally, a monoclonal gammopathy was detected during extensive examination.

[Localized form of psoriasis of the erythema annulare centrifugum type with pustulation].

We report two cases of localized psoriasis of the erythema anulare centrifugum-type with pustulation. Problems of nosological classification and histological differentiation are discussed.

[Aromatic retinoid--oral photochemotherapy (RePUVA) for actinic reticuloid].

RePUVA treatment proved to be more efficient than simple oral photochemotherapy in a patient suffering from actinic reticuloid. This combined therapy may solve some problems of long-term treatment in actinic reticuloid.

[Merkel cell carcinoma (trabecular carcinoma) of the skin].

The Merkel cell carcinoma was first designated some years ago by the descriptive term trabecular carcinoma. Both names refer to a skin tumor occurring in elderly patients. This is another example where ultrastructural differentiating criteria are necessary for a definite diagnosis i.

[Crosti disease (reticulohistiocytoma type Crosti). Light microscopic, ultrastructural, histochemical and immunohistologic findings].

Four patients with lymphoma-like skin diseases of a protracted course and dubious dignity are reported and reviewed together with similar cases of the literature. These cases correspond largely to the entity termed reticulohistiocytoma which was described by Crosti in 1951. The ultrastructural, histochemical, and immunohistological findings indicate tha the tumoral infiltrate consists of a cell population with close similarities to histiocytes.

[Cobb syndrome: association with verrucous angioma, ipsilateral hypertrophy of the extremities and café-au-lait spots].

A case of Cobb syndrome with an 'angioma verrucosum' situated on a segmental skin area corresponding to the cord segment occupied by the spinal angioma is reported. Additionally, this patient had an ipsilateral hypertrophy of the extremities and café au lait spots, anomalies which are only in rare cases associated with the Cobb syndrome.