This study presents findings on the production and analysis of activated carbon (AC), which exhibits a significantly expansive surface area derived from readily available and inexpensive agroforestry waste, specifically coconut shells. The carbon materials displayed encouraging features for electrochemical energy storage applications with a high specific surface area (2920 m g), an ordered mesoporous structure (∼2.5 nm), and substantial electronic conductivity.
View Article and Find Full Text PDFThis study focuses on developing a cost-effective FeO catalyst from oilfield iron waste to create a floating heterogeneous photo-Fenton system with anatase/rutile(A/R) TiO heterophase photocatalyst (cork-FeO@AR-TiO) for treating textile pollution in sunlight. Through controlling sol-gel (SG) microwave heating technique, the A/R ratio of AR-TiO crystal is tuned (A/R ratio = 1.13 and E = 3.
View Article and Find Full Text PDFData assimilation (DA) integrates experimental measurements into computational models to enable high-fidelity predictions of dynamical systems. However, the cost associated with solving this inverse problem, from measurements to the state, can be prohibitive for complex systems such as transitional hypersonic flows. We introduce an accurate and efficient deep-learning approach that alleviates this computational burden, and that enables approximately three orders of magnitude computational acceleration relative to variational techniques.
View Article and Find Full Text PDFWe study fluctuations of the local energy cascade rate Φ_{ℓ} in turbulent flows at scales (ℓ) in the inertial range. According to the Kolmogorov refined similarity hypothesis (KRSH), relevant statistical properties of Φ_{ℓ} should depend on ε_{ℓ}, the viscous dissipation rate locally averaged over a sphere of size ℓ, rather than on the global average dissipation. However, the validity of KRSH applied to Φ_{ℓ} has not yet been tested from data.
View Article and Find Full Text PDFNat Rev Gastroenterol Hepatol
January 2024
Incidence and mortality of colorectal cancer (CRC) are increasing worldwide, suggesting broad changes in the epidemiology of CRC. In this Review, we discuss the changes that are becoming evident, including trends in CRC incidence and mortality by age and birth cohort, and consider the contributions of early-life exposures and emerging risk factors to these changes. Importantly, incidence of CRC has increased among people born since the early 1950s in nearly all regions of the world.
View Article and Find Full Text PDFIntroduction: Screening decreases colorectal cancer incidence and mortality, but uptake in the United States remains suboptimal. Prior studies have investigated the effect of various interventions on overall colorectal cancer screening and stool-based testing, but the effect on colonoscopy-the predominant screening test in the United States-has not been fully examined. We performed a systematic review and meta-analysis to assess the effect of behavioral interventions on screening colonoscopy uptake.
View Article and Find Full Text PDFBackground: Literature on colorectal cancer outcomes in individuals of Middle Eastern and North African (MENA) descent is limited. To address this gap, we estimated five-year colorectal cancer-specific survival by race and ethnicity, including MENA individuals, in a diverse, population-based sample in California.
Methods: We identified adults (ages 18-79 years) diagnosed with a first or only colorectal cancer in 2004 to 2017 using the California Cancer Registry (CCR), including non-Hispanic White, non-Hispanic Black, non-Hispanic Asian, Hispanic, and MENA individuals.
Background: Incidence rates of colorectal cancer (CRC) are increasing among younger adults and in mid-life, implicating exposures in early life as risk factors. We examined the association between in-utero exposure to antibiotics and risk of CRC in adult offspring.
Methods: The Child Health and Development Studies is a prospective cohort of women receiving prenatal care between 1959 and 1966 in Oakland, California, with deliveries through June 1967.
The challenges of consenting for procedures are well documented and are compounded when patients have limited English proficiency (LEP). Standardized video consent has been studied, but research in gastroenterology is limited. We created educational videos in English and Spanish covering the elements of traditional consent for colonoscopy and upper endoscopy.
View Article and Find Full Text PDFClin Gastroenterol Hepatol
February 2023
Background: Young adults diagnosed with colorectal cancer (CRC) comprise a growing, yet understudied, patient population. We estimated 5-year relative survival of early-onset CRC and examined disparities in survival by race-ethnicity in a population-based sample.
Methods: We used the National Cancer Institute's Surveillance, Epidemiology, and End Results program of cancer registries to identify patients diagnosed with early-onset CRC (20-49 years of age) between January 1, 1992, and December 31, 2013.
Background: Epicardial pacemaker placement is often necessary in pacemaker-dependent patients with ongoing device pocket infection or lack of venous access. Pericardial effusion and tamponade are rare but serious complications of this procedure.
Case Summary: A 38-year-old woman presented with nausea, diaphoresis, and hypotension 7 days after epicardial lead placement.
Contrary to decreasing incidence rate of colorectal cancer (CRC) in older adults, incidence rates have nearly doubled in younger adults (age <50 years) in the United States since the early 1990s. A similar increase has been observed across the globe. Despite overall population trends in aging, about 15% of CRCs will be diagnosed in younger adults by 2030.
View Article and Find Full Text PDFDiabetic myonecrosis is a rare complication of diabetes that is typically described in patients with long-standing, uncontrolled diabetes. We report a case in which diabetic myonecrosis presents as an early complication of diabetes. To our knowledge, this is the first report of diabetic myonecrosis observed in an adolescent patient with type 2 diabetes.
View Article and Find Full Text PDFClin Gastroenterol Hepatol
April 2023
Early hepatocellular cancer (HCC) detection is associated with curative treatment and improved survival. The American Association for the Study of Liver Diseases recommends semiannual ultrasound and α-fetoprotein (AFP) in patients with cirrhosis, and those with abnormal results should undergo diagnostic multiphase computed tomography (CT) or magnetic resonance imaging (MRI). The Liver Imaging Reporting and Data System (LI-RADS) was devised to standardize reporting of liver observations in at-risk individuals, ranging from LR-1 ("definitely benign") to LR-5 ("definitely HCC''), with indeterminate observations classified as LR-3 ("intermediate probability of malignancy").
View Article and Find Full Text PDFImportance: Ichthyoses are clinically and genetically heterogeneous disorders characterized by scaly skin. Despite decades of investigation identifying pathogenic variants in more than 50 genes, clear genotype-phenotype associations have been difficult to establish.
Objective: To expand the genotypic and phenotypic spectra of ichthyosis and delineate genotype-phenotype associations.
Background: Screening with fecal immunochemical testing (FIT) reduces colorectal cancer mortality; however, screening remains low in underserved populations. Mailed outreach, including an invitation letter, FIT, and test instructions, is an evidence-based strategy to improve screening.
Aims: To examine screening completion and yield in a mailed outreach program in a safety-net healthcare system.
Objective With the goal of guiding acute management of associated injuries motorcycle trauma patients, this study aims to identify patterns of associated injuries after motorcycle collisions using exploratory factor analysis. Methods We conducted a retrospective review at a Level 1 trauma center of all patients who presented after motorcycle collisions resulting in trauma system activations between July 2, 2002 and December 31, 2013. We performed exploratory factor analysis on this dataset to identify sets of injuries that cluster together.
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