Connecting Data to Value: An Operating Model for Healthcare Advanced Analytics.

Artificial intelligence offers the promise to revolutionize the way healthcare is delivered in the future. To capitalize on the value of advanced analytics and artificial intelligence, organizations must focus on building organizational capabilities. This report shares an operating model for insight and change in healthcare comprising six key components: analytics technology and operations, data governance, change and automation, advanced analytics and insights, analytics literacy and strategy and relationship management.

Connecting Data to Insight: A Pan-Canadian Study on AI in Healthcare.

Across Canada, healthcare leaders are exploring the potential of artificial intelligence and advanced analytics to transform the healthcare system. This report shares a summary of the current state of healthcare analytics across major hospitals and public healthcare agencies in Canada. We present information on the current level of investment, data governance maturity, analytics talent and tools and models being leveraged across the nation.

Developing an Artificial Intelligence-Enabled Health Care Practice: Rewiring Health Care Professions for Better Care.

Artificial intelligence (AI) has the potential to impact almost every aspect of health care, from detection to prediction and prevention. The adoption of new technologies in health care, however, lags far behind the emergence of new technologies. Health care professionals and organizations must be prepared to change and evolve to adopt these new technologies.

Design for a Canadian Digital Health Policy & Practices Observatory.

Canada has struggled to make digital health a reality. We identified 6 key issues that appear to impede progress: 1) an inability to coordinate the actions of a rapidly evolving set of stakeholders, 2) patients who lack the ability and resources to play a meaningful role in health system decision-making, 3) world-class innovation that doesn't reach the market, 4) an inability to kick-start interoperability projects that can catalyze system transformation, 5) an inability to procure early-stage innovative technologies at scale, and 6) an inability to share data seamlessly across organizational silos for patient coordination and care, health system management and research. We propose a set of policies and practices that can help Canada assess, monitor and provide feedback to stakeholders and citizens on how well they are progressing toward seamless digital health.

Galectin-9 binds IgM-BCR to regulate B cell signaling.

The galectin family of secreted lectins have emerged as important regulators of immune cell function; however, their role in B-cell responses is poorly understood. Here we identify IgM-BCR as a ligand for galectin-9. Furthermore, we show enhanced BCR microcluster formation and signaling in galectin-9-deficient B cells.