Characterization of breast lesions using the 3D FIESTA sequence and contrast-enhanced magnetic resonance imaging.

Purpose: To determine whether combining 3D fast imaging employing steady-state acquisition (FIESTA) and T1-weighted contrast-enhanced (CE) sequences could help characterize lesions in 32 women with benign, in situ, or invasive breast lesions. Since FIESTA provides both T1 and T2 information on the same three-dimensional (3D) matrix as high-resolution T1-weighted dynamic data, we aimed to verify whether invasive lesions could be separated from in situ and/or benign lesions using quantitative FIESTA measures of tissue intensity and homogeneity.

Material And Methods: With the use of CE-MRI data, regions of interest (ROIs) were manually delineated in enhancing lesions and on surrounding normal tissue.