Recurrent neck Abscess by Migrating Fishbone Penetrating Thyroid Found in Subcutaneous Tissue: Case Report.

Unlabelled: Extraluminal foreign bodies are rare. Fish bone is the most common foreign body ingested by adults, while coin is the most common foreign body ingested among children. Sharp pricking pain is a sign of sharp foreign body (FB) ingestion.

Tibiocalcaneal fusion using Ilizarov external fixator in total talar extrusion: A case report.

Talar extrusions are the rare extreme case of talar fractures and dislocations which are associated with high-energy trauma. Given the rarity of talar extrusion, no proper treatment protocol has been established. The earlier treatment outcomes have been poor due to the high rate of infection and avascular necrosis.

Optimizing Decision Support Alerts to Reduce Telemetry Duration: A Multicenter Evaluation.

Background:  Telemetry monitoring is crucial for high-risk patients but excessive use beyond practice standards increases costs. Prior studies have shown that electronic health record (EHR) alerts reduce low-value telemetry monitoring. However, specific components of these alerts that contribute to effectiveness are unknown.

JNK inhibitor and ferroptosis modulator as possible therapeutic modalities in Alzheimer disease (AD).

Alzheimer disease (AD) is among the most prevalent neurodegenerative diseases globally, marked by cognitive and behavioral disruptions. Ferroptosis is a form of controlled cell death characterized by intracellular iron accumulation associated with lipid peroxide formation, which subsequently promotes AD initiation and progression. We hypothesized that targeting the ferroptosis pathway may help in AD management.

Functionalised Sodium-Carboxymethylcellulose-Collagen Bioactive Bilayer as an Acellular Skin Substitute for Future Use in Diabetic Wound Management: The Evaluation of Physicochemical, Cell Viability, and Antibacterial Effects.

The wound healing mechanism is dynamic and well-orchestrated; yet, it is a complicated process. The hallmark of wound healing is to promote wound regeneration in less time without invading skin pathogens at the injury site. This study developed a sodium-carboxymethylcellulose (Na-CMC) bilayer scaffold that was later integrated with silver nanoparticles/graphene quantum dot nanoparticles (AgNPs/GQDs) as an acellular skin substitute for future use in diabetic wounds.

Electrovalent effects of sodium carboxymethyl cellulose and hydroxyethyl cellulose on regeneration of empty fruit bunch cellulose to a superabsorbent hydrogel.

The hydrogel regeneration process, involving various cellulose types, results in distinct chemical bonding patterns. Even minor variations in chemical interactions among polymers during regeneration significantly impact properties like hydrogel-forming ability, hydrophilicity, and swelling capacity. This study focuses on regenerating a superabsorbent hydrogel from the interplay of native empty fruit bunch cellulose (EFBC), sodium carboxymethyl cellulose (NaCMC), and hydroxyethyl cellulose (HEC) using epichlorohydrin (ECH) as a crosslinker.

Hydrophobization of nanofibrillated cellulose from Macaranga gigantea for binding of curcumin.

Nanofibrillated cellulose (NFC) has found extensive potential and existing utilizations across various industries. Nonetheless, a notable constraint of NFC lies in its inherent hydrophilic nature, which restricts its suitability for non-aqueous application. This study aims at synthesising hydrophobic NFC through a two-step surface modification by reacting NFC with tannic acid and amine group.

Thermography Research in Diabetic Foot: Insights From a Scopus-Based Bibliometric Study.

Diabetic foot problems are among the most debilitating complications of diabetes mellitus. These problems incur significant economic costs and reduce quality of life. The integration of thermography technology in the screening and management of diabetic foot problems has been proven to be successful in recent years.

Detection of Tetracycline with a CRISPR/Cas12a Aptasensor Using a Highly Efficient Fluorescent Polystyrene Microsphere Reporter System.

CRISPR-based diagnostics use the CRISPR-Cas system -cleavage activity to identify specific target sequences. When activated, this activity cleaves surrounding reporter molecules, producing a detectable signal. This technique has great specificity, sensitivity, and rapid detection, making it an important molecular diagnostic tool for medical and infectious disease applications.

Machine Learning and Gene Editing at the Helm of a Societal Evolution.

The integration of artificial intelligence (AI) and biotechnology, whilst in its infancy, presents significant opportunities and risks, and proactive policy is needed to manage these emerging technologies. Whilst AI continues to have significant and broad impact, its relevance and complexity magnify when integrated with other emerging technologies. The confluence of Machine Learning (ML), a subset of AI, with gene editing (GE) in particular can foster substantial benefits as well as daunting risks that range from ethics to national security.

Dantrolene and coenzyme Q10 as a suggested combination therapy to statin-induced myopathy in high fat diet rats: A possible interference with ROS/ TGF-β / Smad4 signaling pathway.

One of the major hitches for statins' utilization is the development of myotoxicity. Versatile studies reported that the underlining molecular mechanisms including coenzyme Q10 (CoQ10)/ubiquinone depletion, as well as the disturbance in the cytoplasmic Ca homeostasis. Therefore, we investigated the consequences of supplementing CoQ10 and dantrolene, a cytoplasmic Ca reducing agent, in combination with simvastatin.

OMA1 and YME1L as a Diagnostic Panel in Hepatocellular Carcinoma.

Identifying new hepatocellular carcinoma (HCC)-driven signaling molecules and discovering their molecular mechanisms are crucial for efficient and better outcomes. Recently, OMA1 and YME1L, the inner mitochondrial proteases, were displayed to be associated with tumor progression in various cancers; however, their role in HCC has not yet been studied. Therefore, we evaluated the possible role of OMA1/YME1L in HCC staging and discussed their potential role in cellular apoptosis and proliferation.

Ruptured Anterior Tibial Artery Pseudoaneurysm following Ilizarov External Fixator: A Case Report.

Genuine infrapopliteal aneurysms are quite rare, in contrast to pseudoaneurysms. The aetiology of pseudoaneurysms related to external fixation is attributed to various theories, including direct vascular damage due to misplaced pins or wires, overshooting or misguidance during osteotomy, distraction at the corticotomy site during an Ilizarov procedure, and continuous abrasion of the vessel caused by a wire inserted in close proximity to an artery. Arteriography proves valuable in documenting lesions and assessing deeper pseudoaneurysms, particularly when contemplating reconstruction; it plays a crucial role in guiding management decisions.

Crosslinked carboxymethyl cellulose colloidal solution for cotton thread coating in wound dressing: A rheological study.

Cotton thread therapeutic properties as a wound dressing can be enhanced by utilising carboxymethyl cellulose-nanoparticles (CMC/NPs) colloidal solution as a coating solution. Nanoparticles such as graphene oxide (GO), graphene quantum dots (GQD), and silver nanoparticles (AgNP) stability in CMC was investigated through the rheological analysis and UV-Vis spectroscopy of the colloidal solutions. Citric acid (CA) acted as a crosslinker and was utilised to crosslink the colloidal solution with cotton thread.

Optimization of stabilized anaerobic landfill leachate treatment using ozonation with metallic compound using response surface methodology.

Malaysia encounters a consistent rise in the generation of solid waste and leachate on a daily basis. It should also be noted that leachate has a low degree of biodegradability (BOD /chemical oxygen demand [COD]), as shown by its BOD /COD ratio. Its high toxicity levels significantly threaten the environment, water bodies, and human well-being.

Translation and Validation of the Risk Perception on Safety and Health Questionnaire Among Palm Oil Plantation Workers in Terengganu, Malaysia.

Introduction: Occupational safety and health are of utmost importance in the palm oil industry, particularly in Malaysia where palm oil plantation workers face various hazards. This study aimed to translate and validate a risk perception questionnaire specifically designed to assess the perceptions of safety and health risks among palm oil plantation workers in Terengganu, Malaysia.

Methodology: The original risk perception questionnaire, consisting of 22 items, was translated into the local language and culturally adapted.

Effects of carboxymethyl cellulose fiber formations with chitosan incorporation via coating and mixing processes.

To date, the utilization of carboxymethyl cellulose (CMC) fibers are only restricted to weak mechanical application such as wound dressing. Physically, CMC has a weak mechanical strength due to the high hydrophilicity trait. However, this flaw was saved by the extensive number of reactive functional groups, allowing this macromolecule to form linkages with chitosan to ensure its versatility.

Physical properties of the low-cost CZTS absorber layer deposited by spin-coating: effect of the copper concentration associated with SCAPS-1D simulation.

Five samples of copper zinc tin sulfide (CZTS) thin films were deposited by a spin-coating technique at various copper concentrations ranging from 0.5 M to 2.5 M in steps of 0.