Publications by authors named "Zaixin Wu"
Backgrounds: Parkinson's disease (PD) is a common neurodegenerative disorder characterized by motor symptoms and non-motor symptoms. It has been found that intestinal issues usually precede motor symptoms. Microorganisms in the gastrointestinal tract can affect central nervous system through the microbiota-gut-brain axis.
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- A gene called CDT1 is super active in certain cancers, especially in lung adenocarcinoma (LUAD), where it helps control how cells copy themselves.
- Research showed that CDT1 and another gene, E2F2, worked together more when people had LUAD, and reducing CDT1 made cancer cells grow and spread less.
- Studying this in mice, scientists found that lowering CDT1 levels also helped shrink tumors, suggesting that CDT1 could be a target for new cancer treatments.
Background/aim: Endometrial cancer (EC) is a frequent gynecological cancer. Studies have demonstrated that the sensitivity of EC toward 5-fluorouracil (5-FU) chemotherapy has decreased, leading to unsatisfactory treatment effects. There is an urgent need to investigate the reasons for the unsatisfactory treatment of EC with 5-FU.
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