SARS-CoV-2 Evolution: Implications for Diagnosis, Treatment, Vaccine Effectiveness and Development.

The COVID-19 pandemic, driven by the rapid evolution of the SARS-CoV-2 virus, presents ongoing challenges to global public health. SARS-CoV-2 is characterized by rapidly evolving mutations, especially in (but not limited to) the spike protein, complicating predictions about its evolutionary trajectory. These mutations have significantly affected transmissibility, immune evasion, and vaccine efficacy, leading to multiple pandemic waves with over half a billion cases and seven million deaths globally.

Using AI to Improve Radiologist Performance in Detection of Abnormalities on Chest Radiographs.

Background Chest radiography remains the most common radiologic examination, and interpretation of its results can be difficult. Purpose To explore the potential benefit of artificial intelligence (AI) assistance in the detection of thoracic abnormalities on chest radiographs by evaluating the performance of radiologists with different levels of expertise, with and without AI assistance. Materials and Methods Patients who underwent both chest radiography and thoracic CT within 72 hours between January 2010 and December 2020 in a French public hospital were screened retrospectively.

Low back pain indicative of psoas muscle metastasis and bronchopulmonary cancer.

Muscle metastases of bronchopulmonary cancer are rare, notably when they are revealing. They can affect all muscles of the body with a predominance of psoas, diaphragmatic and para-vertebral muscles. We report a case of psoas muscle metastasis revealing bronchopulmonary cancer in a 40-year-old patient with a long history of smoking (30 packs of cigarettes/year) presenting a chronic left low back pain with asthenia and weight loss (15 kg/year).

Air bubbles in the brain: retrograde venous gas embolism in the cavernous sinus.

We present a rare case of cavernous sinuses air embolism occurring after peripheral venous catheterization. This 44-year-old lady followed for idiopathic thrombocytopenic purpura was referred to our service for vomiting and critical headaches after blood transfusion for her thrombocytopenia. Having been submitted to a brain computed tomography, this later showed air bubbles in bilateral cavernous sinuses related to cavernous sinuses gas embolism.

Hydatid pulmonary embolism: An exceptional complication of hydatid disease.

We present an extremely rare case of a young man with hydatid pulmonary embolism caused by a direct invasion of the pulmonary artery by a hydatid cyst. Even if it is a benign parasitic disease, it can lead to serious complications such as arterial, systemic, or multivisceral dissemination or being responsible for an anaphylactic shock. Because of the clinical polymorphism, the diagnosis can be delayed.

Luxatio erecta with greater tuberosity fracture: A case report.

Luxatio erecta is an unusual humeral dislocation. It is frequently associated with neurovascular injuries and concomitant fracture. As such, they require a thorough clinical and imaging evaluation.

Functioning Metastases from Thyroid Papillary Carcinoma in Bone.

Functioning thyroid metastases are a rare cause of hyperthyroidism. Most are follicular carcinoma. Here, we report a case in which a 62-y-old man with a history of right subtotal thyroidectomy for a benign adenoma complained of symptoms of hyperthyroidism associated with left arm pain.

Prevalence and predictors of white-coat hypertension in a large database of ambulatory blood pressure monitoring.

The objective of this study was to determine both the prevalence of white-coat effect and white-coat hypertension (WCH) and which selected clinical variables were predictors of WCH. A total of 2462 patients underwent ambulatory blood pressure monitoring either in borderline hypertension (group 1) or for assessment of antihypertensive treatment (group 2) or for hypotension (group 3). In the overall population 33.

[Factors correlated with left ventricular mass in hypertensive patients].

Unlabelled: Left ventricular hypertrophy (LVH) is an independent risk factor in hypertensive patient.

The Aim: Of our study is to evaluate prospectively the relationship between left ventricular mass and clinical, echocardiographical and ambulatory blood pressure data in hypertensive subjects.

Methods: We studied 88 hypertensive patient who underwent clinical and laboratory investigation, echocardiography and 24 hours ambulatory blood pressure monitoring.

[Percutaneous transluminal renal angioplasty in hypertension].

The aim of our study was assess anatomical and functional results of renal artery angioplasty with and without stenting in 25 hypertensive patients (8 female and 16 male, 42.6 and 61.6 years old respectively) with significative renal artery stenosis (RAS) (atherosclerotic: 22; fibrodysplastic: 3).

[Huge right atrial myxoma revealed by heart failure].

We report a case of 34 years old female with a diagnosis of a big right Atrial myxoma revealed by echocardiography. The treatment consisted on a surgical excision of the tumour under extra corporal circulation. The patient made a good post-operative recovery.