Assessing the impact of Arctic shipping routes on the global container shipping network's connectivity.

Amidst the intensifying impact of climate change, the extension of navigable periods along Arctic Shipping Routes (ASRs) has garnered attention as a maritime route for container vessels. The urgency to comprehend the reverberations of ASRs on the global container shipping network (GCSN) led to the development of the Latitudinal Centrality Index (LCI), which integrates latitude and centrality in maritime analysis. This index evaluates ASRs' influence across 968 port nodes within the GCSN.

Enhancing maritime transportation security: A data-driven Bayesian network analysis of terrorist attack risks.

Maritime terrorist accidents have a significant low-frequency-high-consequence feature and, thus, require new research to address the associated inherent uncertainty and the scarce literature in the field. This article aims to develop a novel method for maritime security risk analysis. It employs real accident data from maritime terrorist attacks over the past two decades to train a data-driven Bayesian network (DDBN) model.

Immune function, gastrointestinal hormone levels, and their clinical significance in patients with gastric ulcers complicated with depression.

Background: Gastric ulcer (GU) is a common digestive tract disease, and medical records of GU combined with depression are increasingly common. Currently, the risk factors and pathogenesis of GU complicated with depression remain unclear. Low immune function and gastrointestinal hormone levels may also be significant risk factors.

Cancer cell-intrinsic XBP1 drives immunosuppressive reprogramming of intratumoral myeloid cells by promoting cholesterol production.

A hostile microenvironment in tumor tissues disrupts endoplasmic reticulum homeostasis and induces the unfolded protein response (UPR). A chronic UPR in both cancer cells and tumor-infiltrating leukocytes could facilitate the evasion of immune surveillance. However, how the UPR in cancer cells cripples the anti-tumor immune response is unclear.

Maritime cybersecurity: are onboard systems ready?

Recent maritime cybersecurity accidents reveal that shipping is facing increased exposure to cyber threats, especially due to the fast-growing digitalisation of the sector, leaving vessels and their onboard systems vulnerable to cyberattacks. This research aims at evaluating the relationship among the critical dimensions influencing cybersecurity performance in the maritime industry. To achieve this, six critical dimensions related to cybersecurity preparedness are first identified through literature review, namely 'regulations', 'company procedures' from a managerial perspective and 'shipboard systems readiness', 'training and awareness', 'human factor' and 'compliance monitoring' at an operation level.

Letter: paying attention to the comorbidities or extraintestinal complications in patients with inflammatory bowel disease during the COVID-19 pandemic.

This article is linked to Hadi et al papers. To view these articles, visit https://doi.org/10.

Assessing the Outbreak Risk of Epidemics Using Fuzzy Evidential Reasoning.

Epidemic diseases (EDs) present a significant but challenging risk endangering public health, evidenced by the outbreak of COVID-19. Compared to other risks affecting public health such as flooding, EDs attract little attention in terms of risk assessment in the current literature. It does not well respond to the high practical demand for advanced techniques capable of tackling ED risks.

The Role of the Prefrontal Cortex and Functional Connectivity during Maritime Operations: An fNIRS study.

Introduction: Watchkeeping is a significant activity during maritime operations, and failures of sustained attention and decision-making can increase the likelihood of a collision.

Methods: A study was conducted in a ship bridge simulator where 40 participants (20 experienced/20 inexperienced) performed: (1) a 20-min period of sustained attention to locate a target vessel and (2) a 10-min period of decision-making/action selection to perform an evasive maneuver. Half of the participants also performed an additional task of verbally reporting the position of their vessel.

Use of evidential reasoning and AHP to assess regional industrial safety.

China's fast economic growth contributes to the rapid development of its urbanization process, and also renders a series of industrial accidents, which often cause loss of life, damage to property and environment, thus requiring the associated risk analysis and safety control measures to be implemented in advance. However, incompleteness of historical failure data before the occurrence of accidents makes it difficult to use traditional risk analysis approaches such as probabilistic risk analysis in many cases. This paper aims to develop a new methodology capable of assessing regional industrial safety (RIS) in an uncertain environment.

Neglected but Important Role of Apolipoprotein E Exchange in Hepatitis C Virus Infection.

Unlabelled: Hepatitis C virus (HCV) is a major cause of chronic liver disease, infecting approximately 170 million people worldwide. HCV assembly is tightly associated with the lipoprotein pathway. Exchangeable apolipoprotein E (apoE) is incorporated on infectious HCV virions and is important for infectious HCV virion morphogenesis and entry.

Advanced uncertainty modelling for container port risk analysis.

Globalization has led to a rapid increase of container movements in seaports. Risks in seaports need to be appropriately addressed to ensure economic wealth, operational efficiency, and personnel safety. As a result, the safety performance of a Container Terminal Operational System (CTOS) plays a growing role in improving the efficiency of international trade.