Fabrication of double crosslinked chitosan/gelatin membranes with Na and pH dual-responsive controlled permeability.

A double crosslinked membrane based on chitosan/gelatin with controlled release properties was synthesized in aqueous system using potassium pyroantimonate and genipin as the ionic crosslinker and covalent crosslinker, respectively. The membranes were characterized using FT-IR, UV-vis spectra, and SEM. In addition, the thermal stability, contact angle, mechanical and controlled release properties were measured.