Hypertension/prehypertension and its determinants in pediatric IgA nephropathy.

Immunoglobulin A nephropathy (IgAN) is a major cause of secondary hypertension (HT) of renal origin - a significant prognostic factor of IgAN. In children, similar to HT, prehypertension (pre-HT) is becoming a significant health issue. However, the role of secondary HT and pre-HT (HT/pre-HT) in the progression of pediatric IgAN remains unclear.

Design, Synthesis, and Bioactivity Evaluation of Novel Isoxazole-Amide Derivatives Containing an Acylhydrazone Moiety as New Active Antiviral Agents.

As a continuation of our efforts to discover and develop "me-better" active molecules, in this study, a series of novel isoxazole-amide derivatives containing an acylhydrazone moiety were synthesized and evaluated for their antiviral activities against tobacco mosaic virus (TMV) and cucumber mosaic virus (CMV). Antiviral bioassays indicated that some of the target compounds exhibited better in vivo antiviral activities against TMV and CMV than those of Ningnanmycin (NNM). Especially, the compound exhibited the best curative, protection, and inactivation activities against TMV and CMV which were superior to those of NNM.

Novel hydrazone derivatives containing pyridine amide moiety: Design, synthesis, and insecticidal activity.

A series of novel hydrazone derivatives containing pyridine amide moiety were designed, synthesized, and evaluated for their insecticidal activity. Bioassays indicated that some of the target compounds exhibited good insecticidal activities against Nilaparvata lugens (N. lugens), Plutella xylostella (P.

[Analysis of volatile oil in herb of pimpinella candolleana by SPME-GC-MS].

Objective: To analyze components of volatile oil from the herb of Pimpinella candolleana.

Method: The components of volatile oil were investigated by SPME-GC-MS.

Result: Sixty-five compounds were identified which accounted for 92.