Publications by authors named "Zai-Li Nu Er Gu"
[Expression Level and Target Gene Prediction of miR-181b in Patients with Chronic Lymphocytic Leukemia].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
June 2020
Objective: To investigate the expression level of miR-181b in CD19+ B lymphocytes of patients with chronic lymphocytic leukemia (CLL), to analyze the relationship between its expression and the prognosis of CLL patients, and to predict the potential target gene of miR-181b in CLL by using bioinformatics.
Methods: Eight-four patients with CLL treated in People's Hospital of Xinjiang Uygur Autonomous Region from June 2013 to June 2018 were selected. and 20 healthy people were selected as control group.
[Application of CpG Oligodeoxynucleotide Immunostimulation in Chromosome Study of Chronic Lymphoblastic Leukemia].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
April 2020
Article Synopsis
- - The study aimed to evaluate the effectiveness of a specific immune-stimulatory method (CpG-ODN DSP30+IL-2) in improving chromosome culture results for chronic lymphocytic leukemia (CLL) cells and to compare findings with other research.
- - Researchers used bone marrow samples from 82 CLL patients, comparing two stimulants: phytohemagglutinin (PHA) and CpG-ODN DSP30+IL-2; results showed a significantly higher success rate in karyotype culture for PHA while the CpG-ODN DSP30+IL-2 group had a higher detection of abnormal karyotypes.
- - The conclusion highlights that using the CpG-OD