Publications by authors named "Zai Ming Lu"

Article Synopsis
  • This study evaluates the combined effectiveness of transarterial chemoembolization (TACE) with PD-(L)1 inhibitors and molecular targeted treatments (MTT) compared to TACE alone in treating hepatocellular carcinoma (HCC).
  • It involved 826 patients, with 376 receiving the combination treatment and 450 undergoing TACE monotherapy, and measured outcomes like progression-free survival (PFS) and overall survival (OS).
  • Findings indicated that the combination treatment significantly improved PFS (9.5 months vs. 8.0 months) and OS (19.2 months vs. 15.7 months) while maintaining a manageable safety profile, especially in patients with advanced HCC.
View Article and Find Full Text PDF

Background: Multiparameter, multimodality F-FDG PET/MRI holds great potential for the diagnosis of cervical cancer based on the correlation between tumor glucose metabolism and imaging parameters.

Purpose: To characterize the heterogeneity of tumor glucose metabolism by evaluating the correlation between F-FDG uptake parameters and multiparametric functional MRI metrics in cervical carcinoma.

Study Type: Retrospective.

View Article and Find Full Text PDF

This study explored the effect of the implant position of stents across the Vater's ampulla on treatment outcomes in patients with lower bile duct obstruction.In the retrospective study, 41 patients with malignant obstruction of the lower bile duct and obstructive jaundice received percutaneous transhepatic biliary placement of bare-metal stents. Basic demographic data on patients, such as sex, age, and primary diseases, and follow-up data, including postoperative complications and jaundice-free survival, were recorded.

View Article and Find Full Text PDF

Purpose: We aimed to evaluate the imaging features of computed tomography (CT) and angiography and the efficacy of transcatheter arterial embolization (TAE) in patients with hemobilia of different iatrogenic causes.

Methods: Thirty patients with hemobilia were divided into two groups according to their iatrogenic causes, i.e.

View Article and Find Full Text PDF
Article Synopsis
  • Hemobilia, which can occur after laparoscopic cholecystectomy (LC), presents diagnostic and treatment challenges, and this study evaluates the role of CT imaging and transcatheter arterial embolization (TAE) in such cases.
  • Fourteen patients with hemobilia were studied, with diagnoses made via endoscopy for 3 patients and contrast-enhanced CT for 11; TAE involved precisely targeting and occluding the bleeding vessel.
  • CT findings included indicators like hematomas and blood clots, and TAE had a 100% success rate without rebleeding, though some patients experienced complications linked to age and timing of the procedures.*
View Article and Find Full Text PDF

Purpose: To assess the imaging features and the management of hemobilia after laparoscopic cholecystectomy (LC).

Materials And Methods: A total of 12 patients who were treated for hemobilia after LC were included in the study. Selective arteriography was performed to find the bleeding artery.

View Article and Find Full Text PDF

This retrospective study investigated the clinical application of sequential therapy with transarterial chemoembolization (TACE) and CT-guided radiofrequency ablation (RFA) using a bipolar needle in treating hepatocellular carcinoma (HCC) tumors of different sizes. The study included patients (N = 46) with HCC from Shengjing Hospital of China Medical University who had received TACE and RFA from November 2012 to November 2013. Eligible patients had an Eastern Cooperative Oncology Group (ECOG) score of 0-1, a Child-Pugh grade of A-B, and no contradictions for TACE and/or RFA.

View Article and Find Full Text PDF

Radiofrequency ablation (RFA), an effective, locally directed therapy for unresectable liver metastases, can improve the survival of patients. As a functional imaging approach, (18)F-fluorodeoxyglucose positron emission tomography ((18)F-FDG PET) or PET-computed tomography (PET-CT) may play a crucial role in the follow-up after RFA. Our objective was to evaluate the diagnostic accuracy of (18)F-FDG PET or PET-CT for the detection of residual tumor following RFA of liver metastases.

View Article and Find Full Text PDF

Background: Morphologic imaging after radiofrequency ablation (RFA) of liver metastases is hampered by an inflammatory response in the ablation margin, making the identification of local tumor progression (LTP) difficult. The aim of this study was to evaluate the efficacy of early (18)F-FDG PET/CT scanning to monitor the effectiveness of RFA in colorectal liver metastases.

Methods: Twelve patients with 20 metastases were treated with RFA for colorectal liver metastases.

View Article and Find Full Text PDF

Objective: To discuss the proliferous rule of bile duct endothelium after the placement of metallic biliary stent.

Methods: The metallic biliary stent was placed at the inferior segment of common bile duct of canine after a percutaneous transhepatic puncture at cholecyst. All the stented dogs were assigned randomly to 4 group including A, B, C and D, each group had been under research for 1 month, 3 months, 12 months and 24 months.

View Article and Find Full Text PDF