Publications by Zahra Zeinali Bardar

Publications by authors named "Zahra Zeinali Bardar"

Iran Biomed J

September 2023

Microvesicles (MVs) from human umbilical cord-derived mesenchymal stem cells (hUCMSCs) show promise as potential biomarkers and treatments for acute myeloid leukemia (AML), particularly affecting the KG-1 leukemic cell line.
The study involved isolating and characterizing hUCMSC-derived MVs and then treating KG-1 cells with different concentrations, resulting in significant increases in apoptosis and autophagy-related gene expression.
Findings suggest that hUCMSC-MVs can effectively induce cancer cell death pathways, pointing towards their potential as a novel therapeutic strategy for AML.

- Zahra Zeinali Bardar's recent research focuses on the therapeutic potential of human umbilical cord mesenchymal stem cell-derived microvesicles (MVs) in treating acute myeloid leukemia (AML).
- The study, published in September 2023, demonstrates that these microvesicles can induce both apoptosis and autophagy in KG-1 leukemic cell lines, highlighting their potential as biomarkers and treatments for AML.
- The research employed flow cytometry to characterize the human umbilical cord-derived mesenchymal stem cells, providing a comprehensive analysis of the biological mechanisms involved.