Tumor volume-adapted SUV as an alternative to SUV for quantification of small lesions in PET/CT imaging: a proof-of-concept study.

Purpose: SUV is a recommended quantification metric except for small lesions. We aimed to assess the averaged standard uptake value (SUV) as an alternative to SUV for small-lesion quantification.

Materials And Methods: NEMA-like phantom images were reconstructed using OSEM, OSEM + PSF, OSEM + TOF and OSEM + TOF + PSF with two post-smoothing Gaussian filters for different background activity levels.