The association between dietary quality index- international and metabolic risk factors in RaNCD cohort study.

Background: Non-communicable diseases (NCDs) are the leading cause of death around the world. The Dietary Quality Index-International (DQI-I) is one of the indicators that shows changes in diet and its association with NCDs. The aim of this study is to measure the association between the DQI-I and major metabolic risk factors.

A Comprehensive Study on the Prognostic Value and Clinicopathological Significance of Different Immune Checkpoints in Patients With Colorectal Cancer: A Systematic Review and Meta-Analysis.

Background: The prognostic significance of immune checkpoint expression in the tumor microenvironment has been widely investigated in colorectal cancers. However, the results of these studies are inconsistent and limited to some immune checkpoints.

Objective: The study aimed to investigate the correlation between different immune checkpoint expression and clinicopathological features and prognostic parameters.

Active motion of tangentially driven polymers in periodic array of obstacles.

One key question about transport of active polymers within crowded environments is how spatial order of obstacles influences their conformation and dynamics when compared to disordered media. To this end, we computationally investigate the active transport of tangentially driven polymers with varying degrees of flexibility and activity in two-dimensional square lattices of obstacles. Tight periodic confinement induces notable conformational changes and distinct modes of transport for flexible and stiff active filaments.

Effects of inertia on conformation and dynamics of tangentially driven active filaments.

Active filamentlike systems propelling along their backbone exist across scales ranging from motor-driven biofilaments to worms and robotic chains. In macroscopic active filaments such as a chain of robots, in contrast to their microscopic counterparts, inertial effects on their motion cannot be ignored. Nonetheless, the consequences of the interplay between inertia and flexibility on the shape and dynamics of active filaments remain unexplored.

Comparative Effect of the Active Substance of Thyme with N-Acetyl Cysteine on Hematological Parameters and Histopathological Changes of Bone Marrow and Liver in Rat Models of Acetaminophen Toxicity.

Acetaminophen has always been at the center of attention as a non-steroidal anti-inflammatory drug, which is generally associated with the serious side effects on liver and the hematological parameters. This study aimed to compare the effect of N-acetyl cysteine (NAC) and thyme extract on rat models of acetaminophen-induced toxicity. The present experimental study was conducted on 48 Wistar rats randomized into six groups, including the control group (no treatment); the Ac group (470 mg/kg of acetaminophen); the Ac + 100Ex, Ac + 200Ex, and Ac + 400Ex groups (acetaminophen + thyme extract at doses of 100, 200, 400 mg/kg); and Ac + NA group (acetaminophen + NAC).

Tim3 and PD-1 as a therapeutic and prognostic targets in colorectal cancer: Relationship with sidedness, clinicopathological parameters, and survival.

Background: Colorectal cancer (CRC) is a heterogeneous disease that complicates predicting patients' prognosis and their response to treatment. CRC prognosis is influenced by the tumor microenvironment (TME). The immune system is a critical component of the TME.

Clinicopathological significance and prognostic role of LAG3 + tumor-infiltrating lymphocytes in colorectal cancer; relationship with sidedness.

Background: It is well-documented that the interplay between tumor-infiltrating lymphocytes (TILs) and tumor cells is a major determining factor in cancer progression. CD45RO seems to be a reliable indicator for predicting prognosis and disease outcome, along with CD3 and CD8 markers. LAG-3 is another important marker that overexpresses on TILs in a variety of cancers and is associated with disease prognosis; however, its prognostic impact is controversial.

Dynamics of Bacteria Scanning a Porous Environment.

It has recently been reported that bacteria, such as Escherichia coli Bhattacharjee and Datta, Nat. Commun. 10, 2075 (2019).

Bottled water quality ranking via the multiple-criteria decision-making process: a case study of two-stage fuzzy AHP and TOPSIS.

Access to healthy drinking water is vital to human health and development. Bottled water consumption has been on the rise in recent years. As several chemical and bacteriological parameters affect bottled water quality, it is difficult to choose the highest-quality bottled water.

Decontamination potential of five native plants in Maharlu Wetland, Iran.

This study investigates the level of toxic trace elements (TTE) in the rhizosphere soil and tissues of five native plants and their phytoextraction/phytostabilization potential growing in Maharlu Lake wetland, in Southern Iran. The study anticipated by determination of 11 potentially TTE concentrations (As, Cd, Co, Cr, Cu, Fe, Mn, Mo, Ni, Pb, and Zn) in the soil, soil extract, and the plants' dry matter (root and shoot). Pollution index (PI), pollution load index (PLI), bioconcentration factor (BCF), bioaccumulation coefficient (BAC), and translocation factor (TF) were applied in the study.

The coronavirus disease 2019: the prevalence, prognosis, and recovery from olfactory dysfunction (OD).

Background: Many patients with coronavirus disease 2019 (COVID-19) complain from olfactory dysfunction (OD). To evaluate the prevalence, prognosis, and recovery from OD in COVID-19 patients.

Material And Methods: In this study, patients with COVID-19 symptoms who were referred to six different tertiary referral centres were recruited after positive results for COVID-19.

Integrating artificial neural network and scoring systems to increase the prediction accuracy of patient mortality and organ dysfunction.

The aim of this study was to develop and compare techniques to increase the prediction accuracy of patient mortality and organ dysfunction in the Intensive Care Units (hereinafter ICU) of hospitals. Patient mortality was estimated with two models of artificial neural network (ANN)-backpropagation (BP) and simplified acute physiology score (SAPS). Organ dysfunction was predicted by coupled ANN self-organizing map (SOM) and logistic organ dysfunction score (LODS) method on the basis of patient conditions.

Psychometric Properties Of The Persian Version Of The Uncivil Behavior In Clinical Nursing Education Among Nursing Students.

Background: Some clinical staff nurses show unprofessional behavior toward nursing students in clinical nursing education that can negatively affect their self-esteem and professionally. Examination of uncivil behavior toward nursing students requires a valid and reliable instrument. Therefore, the goal of the present study was to examine the psychometric properties of the Persian version of the Uncivil Behavior in Clinical Nursing Education (UBCNE) among nursing students.

The prevalence of comorbid depression in patients with diabetes: A meta-analysis of observational studies.

Depression is one of the most common psychiatric disorders in patients with diabetes, which can exacerbate and accelerate adverse diabetes complaints by reducing self-care behaviors and medication adherence. The purpose of this study is to estimate the prevalence of depression in Iranian patients with diabetes. The search was conducted in the databases of Scientific Information Database (SID), MagIran, PubMed, Scopus, Web of Science, and Google Scholar.

Nurses' families' experiences of involvement in nursing errors: A qualitative study.

Background: The most important and irreversible consequence of medical errors is the human impact caused by unintended actions. In a few studies, the significant impact of this error on the private life of healthcare staff have been mentioned, but the problems of the involved nurses' families had been ignored, as of now.

Aims: This study aimed to explain the nurses' families' experiences of involvement in nursing errors.

Dynamics of Active Filaments in Porous Media.

The motion of active polymers in a two-dimensional porous medium is shown to depend critically on flexibility, activity, and degree of polymerization. For a given Péclet number, we observe a transition from localization to diffusion as the stiffness of the chains is increased. Whereas stiff chains move almost unhindered through the porous medium, flexible ones spiral and get stuck.

Health-related quality of life in Iranian patients with type 2 diabetes: An updated meta-analysis.

Diabetes is the most common metabolic causes of increased mortality rate due to its multiple complications. Diabetes, thus, influences patients' quality of life because of its resultant physical disabilities and mental health problems. This study aimed to investigate health-related quality of life among Iranian patients with type 2 diabetes.

A Survey on Massive MIMO Systems in Presence of Channel and Hardware Impairments.

Massive multiple input multiple output (MIMO) technology is one of the promising technologies for fifth generation (5G) cellular communications. In this technology, each cell has a base station (BS) with a large number of antennas, allowing the simultaneous use of the same resources (e.g.

Sesamin imparts neuroprotection against intrastriatal 6-hydroxydopamine toxicity by inhibition of astroglial activation, apoptosis, and oxidative stress.

Parkinson's disease (PD) is one of the most prevalent neurodegenerative disorders in elders. Sesamin is a lignan compound and the active constituent of sesame oil with antioxidant and anti-inflammatory properties. This study was carried out to explore the mechanisms underlying sesamin effect against unilateral striatal 6-hydroxydopamine (6-OHDA) model of PD.

Riluzole ameliorates learning and memory deficits in Aβ25-35-induced rat model of Alzheimer's disease and is independent of cholinoceptor activation.

Alzheimer's disease (AD) is a major global public health concern and social care problem that is associated with learning, memory, and cognitive deficits. Riluzole is a glutamate modulator which has shown to improve memory performance in aged rats and may be of benefit in Alzheimer's disease. In the present study, its beneficial effect on attenuation of learning and memory deficits in Aβ-induced rat model of AD was assessed.

Evaluation of the olfactory bulb volume and olfactory threshold in patients with nasal polyps and impact of functional endoscopic sinus surgery: a longitudinal study.

Background: Debate still persists on the relation between olfactory bulb volume (OBV) and olfactory function. Many studies suggest that olfactory deprivation decreases the OBV. The aim of this study was to compare the olfactory threshold and OBV of patients with nasal polyps to healthy individuals and to evaluate the impact of functional endoscopic sinus surgery (FESS) on OBV and olfactory threshold.

A misdiagnosis led to an extensive skull base surgery: infratemporal tuberculosis mimicking giant cell tumor.

Tuberculosis is a major health problem in developing countries. Tuberculosis of the infratemporal region is not common and the diagnosis could be complicated because of the similarity of the presentation to neoplasm. In our paper, we report a 49 year old male presented with a preauricular mass with extension to parotid in right side of the face.

The efficacy of clarithromycin in patients with severe nasal polyposis.

Although several treatments have been suggested for nasal polyposis, from medical to surgical, there is no standard guideline for the management of this disease. During recent years increasing attention has been directed toward the effects of macrolide antibiotics on chronic sinusitis and nasal polyposis. In this study,  the efficacy of clarithromycin on severe nasal polyposis were examined.