Angio-microRNAs in diabetic foot ulcer-: Mechanistic insights and clinical perspectives.

Diabetic foot ulcers, as one of the chronic wounds, are a serious challenge in the global healthcare system which have shown notable growth in recent years. DFU is associated with impairment in various stages of wound healing, including angiogenesis. Aberrant expression of microRNAs (miRNAs) involved in the disruption of the balance between angiogenic and anti-angiogenic factors, plays a crucial role in angiogenesis dysfunction.

Synthesis, band gap structure and third order non-linear optical properties of zinc tungsten oxide nanocomposite using a single CW laser beam.

In this study, a composite of zinc tungsten oxide nanoparticles (W-ZnO NPs) has been synthesized via mixing NaWO and zinc acetate in water, followed by dropwise addition of NaOH. The synthesized W-ZnO NPs were characterized using measurement methods such as XRD, dynamic light scattering (DLS), Scanning electron microscopy (SEM) and UV-Vis. Also, the results were compared with the pure synthesized ZnO and WO NPs.

Effect of Replacement of Wharton Acellular Jelly With FBS on the Expression of Megakaryocyte Linear Markers in Hematopoietic Stem Cells CD34.

Objective: Animal environments for the growth of stem cells cause the transmission of some diseases and immune problems for the recipient. Accordingly, replacing these environments with healthy environments, at least with human resources, is essential.  One of the media that can be used as an alternative to animal serums is Wharton acellular jelly (AWJ).

Effects of collagen peptide supplementation on cardiovascular markers: a systematic review and meta-analysis of randomised, placebo-controlled trials.

Previous studies have advocated that collagen peptide supplementation (CPS) can positively affect cardiovascular health. However, the widespread impact of CPS on CVD-related markers is not fully resolved. Consequently, the current systematic review and meta-analysis aimed to assess the efficacy of CPS on CVD-related markers.

Eco-friendly synthesis of chromeno[4,3-]chromenes with a new photosensitized WO/ZnO@NH-EY nanocatalyst.

A new heterogeneous photoredox nanocatalyst WO/ZnO@NH-EY (EY: eosin Y) was fabricated and characterized employing some instrumental techniques such as XRD, FT-IR, ICP, TGA, and SEM. The photocatalytic efficiency of the prepared material was investigated in the preparation of various chromeno[4,3-]chromenes a simple and practical method. The chromene derivatives were prepared through the condensation of aromatic aldehydes, dimedone, and coumarin under an open-air atmosphere in the presence of a green LED under solventless conditions.

UV-visible light-induced photochemical synthesis of benzimidazoles by coomassie brilliant blue coated on W-ZnO@NH nanoparticles.

Heterogeneous photocatalysts proffer a promising method to actualize eco-friendly and green organic transformations. Herein, a new photochemical-based methodology is disclosed in the preparation of a wide range of benzimidazoles through condensation of -phenylenediamine with benzyl alcohols in the air under the illumination of an HP mercury lamp in the absence of any oxidizing species catalyzed by a new photocatalyst W-ZnO@NH-CBB. In this photocatalyst, coomassie brilliant blue (CBB) is heterogenized onto W-ZnO@NH to improve the surface characteristics at the molecular level and enhance the photocatalytic activity of both W-ZnO@NH and CBB fragments.

Association of Three Functional Polymorphisms in the NLRP3 Gene with Susceptibility to Rheumatoid Arthritis in the Iranian Population.

Background: Rheumatoid arthritis (RA) is a complex systemic autoimmune disorder with multifactorial nature. Numerous previous studies have shown that several genes are involved in the pathogenesis and increased risk of RA. The Nod-like receptor pyrin domain containing 3 (NLRP3) is involved in the regulation of innate immunity and its upregulation has previously been reported in RA.

Characterization of killed but metabolically active uropathogenic Escherichia coli strain as possible vaccine candidate for urinary tract infection.

Background And Aim: Urinary tract infection (UTI) is the second most frequent infection in human, and uropathogenic Escherichia coli is its most common cause. Although antibiotics are the standard treatment for UTI, they can cause harmful effects on gut microbiome and increase the rate of existing drug-resistant bacteria, which make the vaccine research reasonable. This study was conducted to construct a Killed but Metabolically Active (KBMA) E.

Novel mutation of GATA4 gene in Kurdish population of Iran with nonsyndromic congenital heart septals defects.

Background: The mutations in GATA4 gene induce inherited atrial and ventricular septation defects, which is the most frequent forms of congenital heart defects (CHDs) constituting about half of all cases.

Method: We have performed High resolution melting (HRM) mutation scanning of GATA4 coding exons of nonsyndrome 100 patients as a case group including 39 atrial septal defects (ASD), 57 ventricular septal defects (VSD) and four patients with both above defects and 50 healthy individuals as a control group. Our samples are categorized according to their HRM graph.

The Effect of Stress Management Training through PRECEDE-PROCEED Model on Occupational Stress among Nurses and Midwives at Iran Hospital, Iranshahr.

Introduction: Occupational stress is a major factor in hindering the performance of nurses and midwives and developing physical and mental complications in them. Given that these two groups are in direct contact with patients more than other medical staff and stress management training can be effective in the reduction of occupational stress among the nurses and midwives.

Aim: This study was set out to compare the effect of a PRECEDE-PROCEED based stress management training program on the occupational stress of the nurses and midwives.

Is exclusive breastfeeding and its duration related to cardio respiratory fitness in childhood?

Aims And Objective: This study investigated the effect of breastfeeding on cardio respiratory fitness (CRF) in students of Kermanshah, Iran.

Methods And Materials: In this retrospective cohort study, 246 students with the mean ± SD age of 7.28 ± 0.

The Value of Pre- and Post-Stenting Fractional Flow Reserve for Predicting Mid-Term Stent Restenosis Following Percutaneous Coronary Intervention (PCI).

Measuring fractional flow reserve (FFR) in percutaneous coronary intervention (PCI) has predictive value for PCI outcome. We decided to examine the utility of pre- and post-stenting FFR as a predictor of 6-month stent restenosis as well as MACE (major adverse cardiac events). Pre- and post-stenting FFR values were measured for 60 PCI patients.

Education based on precede-proceed on quality of life in elderly.

Background & Objective: One of the most important challenges in public health is to improve the quality of life in elders. Aging may cause various disorders such as disabilities, high risk conditions and some chronic disease. In this study the effect of educational intervention based on precede-proceed on quality of life in elders was examined.

Effect of education on preventive behaviors of breast cancer in female teachers of guidance schools of Zahedan city based on health belief model.

Background: Breast cancer is one of the most common cancers in females. Methods of screening are the best among early detection methods. The goal of this study is effect of education on preventive behaviors of breast cancer in female teachers of guidance schools of Zahedan city based on health belief model.

Application of the PRECEDE model for controlling iron-deficiency anemia among children aged 1-5, Kerman, Iran.

Iron-deficiency anemia (IDA) is one of the most common nutritional problems in the world. In the Islamic Republic (IR) of Iran, about 30 to 50 percent of women and children have IDA. The purpose of this study was to determine the effect of applying the PRECEDE educational model as a framework for controlling IDA among children aged one to five years old.