Publications by authors named "Zahra Izzi"
Article Synopsis
- This study highlights that while end-stage renal disease (ESRD) patients do not have a significantly higher risk of contracting COVID-19 compared to non-ESRD patients, they do face worse clinical outcomes if infected.
- Key findings indicate that ESRD patients had higher rates of complications, such as stroke and pneumonia, but ESRD status itself was not a significant predictor of death after adjusting for other factors like age and insurance status.
- The research suggests that insurance status played a critical role in mortality rates, indicating health coverage may influence outcomes for COVID-19 patients.
Renal luminal sodium transport is essential for physiological blood pressure control, and abnormalities in this process are strongly implicated in the pathogenesis of essential hypertension. Renal G protein-coupled receptors (GPCRs) are critical for the regulation of the reabsorption of essential nutrients, ions, and water from the glomerular filtrate. Recently, we showed that GPCR 37L1 (GPR37L1) is expressed on the apical membrane of renal proximal tubules (RPT) and regulates luminal sodium transport and blood pressure by modulating the function of the sodium proton exchanger 3 (NHE3).
View Article and Find Full Text PDFAlterations of gut microbial pathways and virulence factors in hemodialysis patients.
Front Cell Infect Microbiol
September 2022
Alterations in gut microbiota might contribute to uremic toxicity and immune dysregulation in patients with end-stage renal disease. Hemodialysis patients are prone to infection and higher mortality following sepsis. The virulence factors in the gut metagenome have not been well studied in hemodialysis patients, which could be employed by microorganisms to successfully thrive and flourish in their hosts.
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