Publications by authors named "Zahra Hajimohammadi"
The 3.7 kb deletion is the most common known mutation in the α-globin gene cluster worldwide. The aim of this study is to investigate the most common types of 3.
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- * The study used 112 samples from Iran to evaluate a new multiplex PCR method that identifies key deletions in the alpha-globin gene cluster associated with the disorder.
- * Statistical analysis showed significant differences in genetic markers, indicating that the new method effectively detects common deletions, though further research with more samples is recommended for improved accuracy.
Background: Dyskeratosis congenita (DC) is a rare disease and is a heterogenous disorder, with its inheritance patterns as autosomal dominant, autosomal recessive, and X-linked recessive. This disorder occurs due to faulty maintenance of telomeres in stem cells. This congenital condition is diagnosed with three symptoms: oral leukoplakia, nail dystrophy, and abnormal skin pigmentation.
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