Publications by authors named "Zahra Aganj"
Background: Following antigen stimulation, naive CD4 T cells differentiate into different T helper (Th) subsets characterized by lineage-specific transcriptional factors and cytokines. The balance between cytokines from Th1 and Th2 cells is disrupted in autoimmune disorders, asthma, and allergic reactions. Crocin, the major carotenoid of saffron, has anti-inflammatory properties.
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- Drug resistance poses a major challenge in effective cancer therapy, often leading to disease relapse after initial chemotherapy success.
- Epithelial-mesenchymal transition (EMT) is a crucial biological process that helps cancer cells become more aggressive and resistant to treatment by changing their characteristics.
- Natural products show promise as safer cancer treatment options by potentially reversing EMT and addressing drug resistance through their ability to interfere with the underlying molecular mechanisms involved.