The site of Tepe Hissar (Iran) experienced widespread cultural and economic changes during the Chalcolithic and Bronze Ages (5 to the 2 millennium B.C.).
View Article and Find Full Text PDFIn order to develop effective anti-cholinesterase compounds, a novel series of pyrano[3',4':5,6]pyrano[2,3-b]quinolinones were designed, synthesized, and evaluated in vitro against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). All derivatives showed very good AChE inhibitory (AChEI) activity (IC = 0.37-5.
View Article and Find Full Text PDFPseudomonas aeruginosa is an important opportunistic human pathogen that causes a wide variety of severe nosocomial infections. Type IV pili of P. aeruginosa are made up of polymerized pilin that aids in bacterial adhesion, biofilm formation and twitching motility.
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