Publications by authors named "Zahi Dagan"
Background: Acetaminophen is the most common drug involved in pediatric poisonings, both intentionally and accidentally, and is the leading cause of acute liver failure among all age groups.
Objectives: To define the characteristics of patients admitted to a pediatric emergency department (ED) where serum acetaminophen concentrations were measured, and to determine which variables are associated with significant risk of acetaminophen toxicity.
Methods: Acetaminophen serum concentrations were measured, in a retrospective case series, of patients younger than 18 years who had been admitted to the ED at Shamir Medical Center between 1 January 2008 and 31 December 2015.
It has been suggested that oxidative stress is a potential mechanism for vancomycin-induced nephrotoxicity and hyperbaric oxygen therapy (HBO) has been shown to be effective in treating renal toxicity that has been pharmacologically induced in animal models. The aim of this study was to investigate the effect of HBO therapy on vancomycin-induced nephrotoxicity in rats. The study group comprised 36 Sprague Dawley male rats.
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- Levetiracetam is a medication used as an additional treatment for various seizure types, but there's limited research on its effects in children with hard-to-treat epilepsy.
- A study reviewed medical records of 50 children to analyze the relationship between blood levels of levetiracetam and its effectiveness or side effects.
- The findings showed no significant link between serum levels, dosage, effectiveness, or adverse effects, suggesting routine serum concentration monitoring may not be necessary for all pediatric patients on levetiracetam.
Article Synopsis
- Childhood obesity is a growing global health issue; a study focused on adolescents in a dormitory school aimed to improve their dietary habits and physical activity to combat obesity.
- The study involved 36 obese adolescents and a control group, with a 6-month intervention that included weekly nutrition counseling and bi-weekly exercise sessions, measuring various health indicators before and after the intervention.
- Despite a significant decrease in BMI in the intervention group, overall compliance was low, indicating the need for a more integrated approach involving parents and the school to effectively promote healthy lifestyle changes.
No retinal hemorrhages were detected in any of 100 consecutive children aged 3 months to 2 years with severe, persistent coughing (0 of 100, 95% CI: 0%- 3%). Therefore, if one finds retinal hemorrhage in infants and young children with cough, child abuse must be excluded.
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