Visual field changes in methotrexate therapy. Case report and review of the literature.

Purpose: To present a unilateral central visual field defect in a patient with psoriatic arthritis treated with Methotrexate and folic acid supplement, probably induced by toxic posterior optic neuropathy. The scotoma incompletely resolved after cessation of Methotrexate (MTX) therapy.

Methods: Serial fundoscopic, perimetric and electrophysiological examination as well as comprehensive neurological investigation including lumbar puncture, carotid sonography, electroneurography, and MRI of the brain.

High-grade malignant B-cell lymphoma of the retina in a patient with concomitant gastric MALT lymphoma.

Purpose: To report the unexpected finding of a primary retinal B-cell lymphoma in a patient with previous breast carcinoma and subsequent lymphoma of the stomach.

Methods: Histopathologic and immunohistochemical findings in the enucleated eye are described in conjunction with clinical features and investigations.

Results: An 80-year-old woman with previous breast cancer presented with moderate loss of vision associated with vitreous opacities, circumpapillary retinal haemorrhages, and attenuated retinal vessels in her left eye.

Jesus and the eye: New Testament miracles of vision.

Purpose: To compile and appraise the accounts of the miracles of vision in the New Testament.

Methods: We carried out a critical analysis of the compilation of ocular miracles using past medical knowledge and historical reconstruction based on the accounts of the apostles and of various historians living in the first three centuries ad.

Results: Three blind adult male beggars residing on three different street locations were described.

Loa loa macrofilariasis in the eyelid: case report of the first periocular subcutaneous manifestation in Germany.

Purpose: We report a case of periocular subcutaneous macrofilariasis as an initial sign of a systemic Loa loa infection.

Methods: Thorough history, eye examination and surgical intervention. Parasitological and serological analysis.

Recurrent retinal vein occlusion after playing a wind instrument.

Purpose: To present a complication of repeated Valsalva maneuver.

Methods: Case report with serial intravenous fluorescein angiography and comprehensive workup for coagulopathies.

Results: After playing strenuous musical pieces, a solo trombonist suffered within 1 year three attacks of visual loss in the right eye; he had two attacks of inferior hemi-central retinal vein occlusion 2 months apart, followed by central retinal vein occlusion 10 months later.