First-in-Human Study of the Saranas Early Bird Bleed Monitoring System for the Detection of Endovascular Procedure-Related Bleeding Events.

Objectives: To evaluate the safety and accuracy of the Early Bird Bleed Monitoring System (EBBMS; Saranas) for the detection of access-site related bleeds in humans undergoing endovascular procedures.

Background: Bleeding complications after endovascular procedures are frequent and associated with poor prognosis. The EBBMS is a novel technology designed to detect in real time the onset, progression, and severity of internal bleeds.

Implantable cardioverter-defibrillator prescription in the elderly.

Background: Because sudden cardiac death increases with age, implantable cardioverter-defibrillators (ICDs) might greatly benefit the elderly. However, elderly patients are underrepresented in clinical trials, and comorbid conditions may attenuate benefit.

Objective: The purpose of this study was to examine ICD prescription in the elderly.

Increased base rate of atrial pacing for prevention of atrial fibrillation after implantation of a dual-chamber pacemaker: insights from the Atrial Overdrive Pacing Study.

Aims: Different pacing sites and various algorithms have been utilized to prevent atrial fibrillation (AF) in pacemaker recipients. However, the optimal pacing rate settings have not yet been established. In this randomized, prospective, multicentre, single-blinded, cross over study, rate-adaptive pacing at a high base rate (BR) in patients, age 60 years or above, or a history of paroxysmal AF, who underwent dual-chamber (DDD) pacemaker implantation for standard pacing indications, was evaluated for prevention of AF.

Effect of short pulse width programming in AutoCapture devices.

Pacing chronaxie can increase over time. The impact of a short pulse duration on threshold (THR) variations, frequency of noncapture episodes, and overall patient safety has not been fully studied. AutoCapture (AC) pacemakers are capable of memorizing THR trends and loss of capture (LOC) episodes.

Rhythm classification by correlation-waveform morphology analysis of atrial and ventricular electrogram signals.

We tested the use of correlation-waveform analysis (CWA) of atrial and ventricular electrograms (EGMs) to distinguish ventricular tachycardia (VT) from supraventricular tachycardia (SVT). Patients undergoing electrophysiologic testing were enrolled. EGMs recorded during induced tachycardias were compared with EGMs recorded during sinus and paced rhythms, taken as templates, by assigning a CWA percent-match (CPM) score.

AutoCapture with dual-coil leads of implantable cardioverter defibrillator.

AutoCapture (AC) can confirm ventricular capture with true bipolar single coil leads of implantable cardioverter defibrillators (ICD). The compatibility of AC with a new, true bipolar, dual-coil ICD lead needed to be evaluated. This multicenter study enrolled 46 patients (69 +/- 10 years, 37 men) undergoing ICD implantation.

Use of the AutoCapture Pacing System with implantable defibrillator leads.

Introduction: Previous studies using various bipolar pacemaker leads have shown that the AutoCapture (AC) Pacing System is able to verify ventricular capture and regulate pacing output, increasing patient safety with respect to unexpected threshold changes and potentially prolonging device longevity. An increasing number of patients with implantable cardioverter defibrillators (ICDs) require ventricular pacing that contributes to a shortening of longevity of these systems. This prospective study tested the compatibility of the AC system with bipolar ICD leads.