Towards digital diagnosis of malaria: How far have we reached?

The need for precise and early diagnosis of malaria and its distinction from other febrile illnesses is no doubt a prerequisite, primarily when standard rapid diagnostic tests (RDTs) cannot be totally relied upon. At the time of disease outbreaks, the pressure on hospital staff remains high and the chances of human error increase. Therefore, in the era of digitalisation of medicine as well as diagnostic approaches, various technologies such as artificial intelligence (AI) and machine learning (ML) should be deployed to further aid the diagnosis, especially in endemic and epidemic situations.

Angiotensin-converting enzyme gene polymorphism in patients with psoriatic arthritis.

To investigate the frequency of angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism genotypes in adults with psoriatic arthritis (PsA), a heterogeneous chronic disease with autoimmune pathology. ACE gene I/D polymorphism influences the plasma and tissue levels of ACE and has an involvement in inflammatory mechanism. The frequency of ACE gene I/D polymorphism genotypes was determined in 51 adults with PsA from Kuwait, and compared to that in 100 ethnically matched healthy controls using polymerase chain reaction.

Angiotensin converting enzyme gene insertion-deletion polymorphism is associated with juvenile rheumatoid arthritis.

Objective: To investigate the incidence of angiotensin converting enzyme (ACE) gene insertion-deletion (I/D) polymorphism genotypes in children with juvenile rheumatoid arthritis (JRA), a heterogeneous chronic disease with autoimmune pathology. ACE gene I/D polymorphism influences the plasma and tissue levels of ACE and has an involvement in inflammatory mechanisms.

Methods: The incidence of ACE gene I/D polymorphism genotypes was determined in 82 children with JRA from Kuwait and compared to that in 48 ethnically matched healthy controls using polymerase chain reaction.