Renal Cell-Like Adenocarcinoma of Nasal Cavity: A Rare Entity Deserving Elucidation.

Unlabelled: Sino-nasal malignancies are extremely rare accounting < 1% of all malignancies and < 3% of aero-digestive tract tumors. Their surgical pathology is extremely challenging due to the enormous heterogeneity. Few of these sino-nasal tumors may possibly present histologically as clear cell neoplasm.

Advanced fabrication techniques for polymer-metal nanocomposite films: state-of-the-art innovations in energy and electronic applications.

Polymer-metal nanocomposites are a fascinating class of materials that synergize the distinct properties of polymers and metals. Incorporating metal nanofillers into polymer matrices significantly enhances electrical conductivity, mechanical strength, and thermal stability through intricate chemical interactions. This review provides an in-depth understanding of current and emerging fabrication techniques for polymer-metal nanocomposite films, with a particular focus on advanced chemical mechanisms and the resulting material properties.

Morphological, Physiological, and Molecular Responses to Heat Stress in Brassicaceae.

Food security is threatened by global warming, which also affects agricultural output. Various components of cells perceive elevated temperatures. Different signaling pathways in plants distinguish between the two types of temperature increases, mild warm temperatures and extremely hot temperatures.

Defining Renal Recovery in Patients With Hepatorenal Syndrome-Acute Kidney Injury: Experience From North American Studies.

Introduction: The degree of improvement in serum creatinine (SCr) has previously been suggested as a sensitive indicator of treatment response in patients with hepatorenal syndrome-acute kidney injury (HRS-AKI), while HRS reversal remains the primary endpoint in clinical trials.

Methods: A total of ≥ 30% SCr improvement was analyzed as an exploratory prespecified endpoint in the CONFIRM trial. In this post hoc analysis, intent-to-treat population data from three Phase 3 studies (OT-0401, REVERSE, and CONFIRM) conducted in North America in patients with HRS-AKI were pooled to assess the incidence of > 30% improvement in SCr and its association with clinical outcomes.

LSSF-Net: Lightweight segmentation with self-awareness, spatial attention, and focal modulation.

Accurate segmentation of skin lesions within dermoscopic images plays a crucial role in the timely identification of skin cancer for computer-aided diagnosis on mobile platforms. However, varying shapes of the lesions, lack of defined edges, and the presence of obstructions such as hair strands and marker colours make this challenge more complex. Additionally, skin lesions often exhibit subtle variations in texture and colour that are difficult to differentiate from surrounding healthy skin, necessitating models that can capture both fine-grained details and broader contextual information.

Spatial distribution, ecological and human health risks of potentially toxic elements (PTEs) in river Ravi, Pakistan: A comprehensive study.

Significant quantities of potentially toxic elements have been and are still being discharged into Pakistan's rivers through natural sources and anthropogenic activities. The present study provides a comprehensive study of potentially toxic element contamination in the water and sediment of the Ravi River, Pakistan. The research aims to examine the extent of pollution, its ecological risks, and the potential human health impacts through detailed geospatial analysis and statistical correlation.

Advances in MXene-based technologies for the remediation of toxic phenols: A comprehensive review.

The pressing global issue of organic pollutants, particularly phenolic compounds derived primarily from industrial wastes, poses a significant threat to the environment. Although progress has been made in the development of low-cost materials for phenolic compound removal, their effectiveness remains limited. Thus, there is an urgent need for novel technologies to comprehensively address this issue.

Altering electronic structure of nickel foam supported CoNi-based oxide through Al ions modulation for efficient oxygen evolution reaction.

Developing highly active and durable non-precious metal-based electrocatalysts for the oxygen evolution reaction (OER) is crucial in achieving efficient energy conversion. Herein, we reported a CoNiAlO/NF nanofilament that exhibits higher OER activity than previously reported IrO-based catalysts in alkaline solution. The as-synthesized CoNiAlO/NF catalyst demonstrates a low overpotential of 230 mV at a current density of 100 mA cm, indicating its high catalytic efficiency.

Anderson Localization of Phonons in Thermally Superinsulating Graphene Aerogels with Metal-Like Electrical Conductivity.

In the quest to improve energy efficiency and design better thermal insulators, various engineering strategies have been extensively investigated to minimize heat transfer through a material. Yet, the suppression of thermal transport in a material remains elusive because heat can be transferred by multiple energy carriers. Here, the realization of Anderson localization of phonons in a random 3D elastic network of graphene is reported.

Effects of oxygen vacancies and interfacial strain on the metal-insulator transition of VO nanobeams.

The role of oxygen vacancies and interfacial strain on the metal-insulator transition (MIT) behavior of high-quality VO nanobeams (NBs) synthesized on SiO/Si substrates employing VO as a precursor has been investigated in this research. Selective oxygen vacancies have been generated by argon plasma irradiation. The MIT is progressively suppressed as the duration of plasma processing increases; in addition, the temperature of MIT () drops by up to 95 K relative to the pristine VO NBs.

Identification of the odorant binding proteins of Western Flower Thrips (), characterization and binding analysis of with molecular modelling, molecular dynamics simulations and a confirmatory field trial.

Olfactory systems are indispensable for insects as they, including Western Flower Thrips (), use olfactory cues for ovipositing and feeding. use odorant binding proteins (OBPs) to transport semiochemicals to odorant receptors to induce a behavioural response from the sensillum lymph of the insect's antennae. This study identifies four OBPs of and analyses their expression at three stages of growth: larvae, adult males and adult females.

Improving value delivery in living donor kidney transplant through process improvement.

Introduction: Living donor kidney evaluation has substantial time variations with significant intercenter variation. One-day donor evaluation has shown to be clinically efficient and improve transplant rates. However, patients' perception of 1-day evaluation is unknown.

Lipid-based Nutritional Supplement Impact on Energy Intake, Appetite, Glucose and Insulin Levels in Under-Weight Pregnant and Lactating Women with Preeclampsia.

Objective: To investigate the response of nutritional supplement (LNS-PLW) on appetite score, energy intake, insulin and glucose levels in preeclamptic women.

Design & Participants: Sixty under-weight preeclamptic primigravida were divided into two groups randomly and provided LNS-PLW/Placebo in the fasted state. Blood samples were collected at fasting state, after 30mins of supplementation, "ad libitum buffet" breakfast and lunch for glucose and insulin levels.

The analysis of a new fractional model to the Zika virus infection with mutant.

We present a new mathematical model to analyze the dynamics of the Zika virus (ZV) disease with the mutant under the real confirmed cases in Colombia. We give the formulation of the model initially in integer order derivative and then extend it to a fractional order system in the sense of the Mittag-Leffler kernel. We study the properties of the model in the Mittag-Leffler kernel and establish the result.

The Effectiveness of Prehospital Administration of Tranexamic Acid in Reducing Mortality in Trauma Patients: An Overview.

Tranexamic acid (TXA) is an antifibrinolytic drug that reduces bleeding by inhibiting plasminogen activation and fibrin clot degradation. Its role in prehospital trauma management remains unclear. This article aims to systematically review the current evidence on the effect of prehospital TXA administration on mortality in adult and pediatric trauma patients.

Investigating the effect of curing temperature on the corrosion resistance of epoxy-based composite coatings for aluminium alloy 7075 in artificial seawater.

Araldite LY5052 epoxy resin and Aradur HY5052 hardener were used in a ratio of 100 : 38 to produce composite coatings containing 0.05 proportion of functionalized SiO. Coating samples were cured at curing temperatures of 60, 80, 100, 120, and 140 °C.

Genome-wide identification and comparative in-silico characterization of β-galactosidase (GH-35) in ascomycetes and its role in germ tube development of Aspergillus fumigatus via RNA-seq analysis.

β-galactosidase (Lactase), an enzyme belonging to the glycoside hydrolase family causing the hydrolysis and trans-glycosylation of β-D-galactosides, has a vital role in dairy industries. The current investigation emphasizes on in-silico identification and comparative analysis of different fungal lactases present in Aspergillus fumigatus, Aspergillus oryzae, Botrytis cinerea, and Fusarium fujikuroi. Prediction of motifs and domains, chromosomal positioning, gene structure, gene ontology, sub-cellular localization and protein modeling were performed using different bioinformatics tools to have an insight into the structural and functional characteristics of β-galactosidases.

Revisiting the inhibitory potential of protein kinase inhibitors against NEK7 protein via comprehensive computational investigations.

The NEK7 protein is required for spindle formation, cell division, and the activation of the NLRP3 inflammasome receptor. The aberrant expression of NEK7 has been implicated to the growth of metastasis and severe inflammatory conditions like rheumatoid arthritis, liver cirrhosis, and gout. An emergent target for the development of anti-cancer drugs is NEK7.

Photosynthetic activity and metabolic profiling of bread wheat cultivars contrasting in drought tolerance.

The rapid increase in population growth under changing climatic conditions causes drought stress, threatening world food security. The identification of physiological and biochemical traits acting as yield-limiting factors in diverse germplasm is pre-requisite for genetic improvement under water-deficit conditions. The major aim of the present study was the identification of drought-tolerant wheat cultivars with a novel source of drought tolerance from local wheat germplasm.

Ferritin screening and Iron treatment for maternal anemia and fetal growth restriction prevention - A multicenter randomized controlled trial (FAIR Study).

Background: Non-anemic iron deficiency precedes iron deficiency anaemia and has an estimated prevalence of 1-2 billion worldwide. Few studies have comprehensively researched the idea of treating non-anemic iron deficiency (NAID) with iron to improve the outcome of the mother and the offspring.

Methods And Analysis: FAIR will be a multicenter randomized controlled trial that will be conducted in multiple clinical academic obstetrics units in Lahore (including Services Institute of Medical Sciences, Lahore, Allama Iqbal Medical College, Lahore and Fatima Jinnah Medical University).

Photosynthesis and Salt Exclusion Are Key Physiological Processes Contributing to Salt Tolerance of Canola ( L.): Evidence from Physiology and Transcriptome Analysis.

Plant salt tolerance is controlled by various physiological processes such as water and ion homeostasis, photosynthesis, and cellular redox balance, which are in turn controlled by gene expression. In the present study, plants of six canola cultivars (DGL, Dunkled, Faisal Canola, Cyclone, Legend, and Oscar) were evaluated for salt tolerance by subjecting them to 0 or 200 mM NaCl stress. Based on growth, cultivars DGL, Dunkled, and Faisal Canola were ranked as salt tolerant, while cultivars Cyclone, Legend, and Oscar were ranked as salt-sensitive ones.