Publications by authors named "Zafar Sheikh"

Article Synopsis
  • * Rare complications can arise from PTC, including unusual cases of brain metastasis, which indicate a more aggressive disease, despite PTC typically not spreading beyond local lymph nodes.
  • * This case report highlights the complexities of diagnosing and managing neurological symptoms in a PTC patient, emphasizing the need for thorough diagnostic assessments due to potential confusion with primary brain tumors and the implications for patients with prior cancers.
View Article and Find Full Text PDF

Renal plasmacytoma is a rare extramedullary manifestation of plasma cell neoplasms (PCN). We present the case of a 62-year-old male with a history of relapsed refractory multiple myeloma (MM) who developed secondary renal plasmacytoma after an eight-year remission period. Radiological findings on plain CT raised concern for the most common renal malignancy, i.

View Article and Find Full Text PDF

Scabies, a human skin infestation caused by the ectoparasitic mite var. , affects more than 200 million people globally. The prevailing knowledge of the disease process and host immune response mechanisms is limited.

View Article and Find Full Text PDF

Pseudopapillary tumor (SPT) is a rare primary pancreatic neoplasm of uncertain origin and low malignant potential that typically affects young females, mostly in their third decade of life. There are only a few reports on fine needle aspiration (FNA) cytology diagnosis of this neoplasm. We report one such case which was diagnosed based on cytomorphologic and immunocytochemical features on endoscopic ultrasound (EUS) guided FNA smears.

View Article and Find Full Text PDF

Background: Infiltration of tumors by dendritic reticulum cells (DRC) reflects the host immune defense mechanism. We observed three breast carcinomas cases with dense tumor-infiltrating DRC and lymphocytes in fine-needle aspiration (FNA) smears, leading to cytodiagnosis or differential diagnosis of dendritic reticulum cell sarcoma (DRCS). An attempt was made to find out the reason behind such an erroneous interpretation.

View Article and Find Full Text PDF

Introduction: Anterior approach provides excellent visualization and access to the anterior thoracic spine. It may be used alone, in combination with a posterior midline approach or in a staged or sequential fashion.

Aims: To analyse our institutional experience in transthoracic approaches and to determine the safety and benefit of this approach in our patient series.

View Article and Find Full Text PDF

A small percentage of nodular lymphocytic predominant Hodgkin lymphoma (NLPHL) progresses to diffuse large B-cell lymphoma (DLBCL). There have also been rare reports of gray zone lymphoma with features intermediate between classical Hodgkin lymphoma (CHL) and DLBCL. We report a very rare case of composite lymphoma (CHL and NLPHL) progressing to DLBCL, and highlight the diagnostic difficulty faced during its fine-needle aspiration (FNA) cytology diagnosis.

View Article and Find Full Text PDF

Background:: Different topical therapies are being used for treating molluscum contagiosum. Potassium hydroxide in varying solution strengths with irritant reaction on the skin can help in eliminating the infection. It is cheap, easily available, can be easily applied at home, with good safety profile and cost effectiveness.

View Article and Find Full Text PDF

Langerhans cell histiocytosis (LCH) can be associated with a variety of malignant neoplasms, the most common being malignant lymphoma, especially Hodgkin's lymphoma (HL). In this report, we describe the fine needle aspiration (FNA) cytologic features of a case with concurrent LCH and HL in a lymph node. A 20-year-old man presented with an enlarged left upper cervical lymph node.

View Article and Find Full Text PDF

Objective: To determine the efficacy of clarithromycin in the treatment of Pityriasis Rosea (PR).

Study Design: Double blind randomized controlled trial.

Place And Duration Of Study: Dermatology OPD, Military Hospital, Rawalpindi, from July 2008 to July 2009.

View Article and Find Full Text PDF

Objective: Kikuchi-Fujimoto disease (KFD) is a self-limiting disorder which usually affects young women. There are only a few studies on pediatric KFD patients and their fine-needle aspiration (FNA) cytodiagnosis. We report a series of pediatric KFD patients diagnosed by FNA cytology and compare them with adults.

View Article and Find Full Text PDF

Background: Hepatitis C Virus (HCV) has estimated affected nearly 3% of the world population. Studies in Pakistan have shown a somewhat higher prevalence. The objective of this study was to determine the frequency of hepatitis C virus infection in patients with dermatological disorders, known to be associated with HCV infection.

View Article and Find Full Text PDF

Exclusive reports on fine needle aspiration (FNA) cytodiagnosis of T-cell-rich B-cell lymphoma (TCRBCL) are scarce in literature. This report reflects the diagnostic difficulties associated with cytodiagnosis of this rare variant of diffuse large B-cell lymphoma. The study is based on 11 cases with age ranging from 16 to 63 years and a median of 50 years.

View Article and Find Full Text PDF

Objective: During routine fine needle aspiration cytodiagnosis of papillary thyroid carcinoma (PTC), a number of cases are diagnosed as suspicious; or it is suggested that PTC or a neoplasm be ruled out by histopathology. Since these diagnostic labels are likely to put the clinicians in a difficult situation while planning the management, this study aims to find out how much the surgeon should read from these reports.

Materials And Methods: The patients were divided into two groups.

View Article and Find Full Text PDF

Sarcoidosis is a multisystem granulomatous disorder of unknown etiology. The fine needle aspiration cytologic features are noncaseating granulomas, lymphocytes and multinucleated giant cells (MGCs) with or without asteroid bodies. A 41-year-old man, an ex-smoker, presented to the Pulmonary Division of Mubarak Al-Kabeer Hospital, Safat, Kuwait, with chief complaints of dyspnea, wheezing and persistent cough of 6 weeks' duration.

View Article and Find Full Text PDF

Objective: To report a case of right posterior subcapsular cataract induced by 3-monthly depot luteinizing hormone-releasing hormone (LHRH) analogue therapy in a patient with early prostate cancer.

Case Presentation: A 52-year-old male with static myopia of several years' duration was given a 3-month depot LHRH analogue (goserelin 10.8 mg) as part of neoadjuvant treatment for early prostate cancer.

View Article and Find Full Text PDF

Objective: The aim of this study was to determine the incidence of squamous cell abnormalities in cervical cytology in Mubarak Al-Kabeer Hospital, Kuwait, and to document any change in the pattern of these lesions.

Materials And Methods: Over a 13-year period (1992-2004), 86,434 cervical smears were studied in Mubarak Al-Kabeer Hospital, Kuwait. Conventional Pap smears were first examined by cytotechnicians and finally reported by cytopathologists.

View Article and Find Full Text PDF

Background: Fine needle aspiration (FNA) cytologic diagnosis of toxoplasmic lymphadenitis with demonstration of a tissue cyst containing bradyzoites has been very rarely reported.

Case: A 17-year-old female presented with a mobile, painless, 2-cm-diameter swelling over the right suprascapular area. Clinical diagnosis was lipoma.

View Article and Find Full Text PDF

Objective: To retrospectively analyze the role of ultrasound (US) imaging and US-guided fine needle aspiration cytology in the diagnosis and management of abdominal hydatid cyst disease (HCD).

Subjects And Methods: The medical records of 55 diagnosed cases of HCD seen between January 1986 and December 2000 at Mubarak Al-Kabeer Hospital and Al-Amiri Hospital in Kuwait were reviewed for demographic and clinical data, including radiology and serology. The US findings of the patients were classified into four types as follows: type I: single or multiple well-defined cysts, with or without detached or collapsed wall and with or without echogenic contents; type II: single or multiple cysts with peripheral cysts, with or without echogenic contents; type III: solid or semisolid lesions, and type IV: cysts with calcified walls.

View Article and Find Full Text PDF