Proteinaceous lymphadenopathy (PLD) is a rare poorly defined, underrecognized entity of uncertain etiology, characterized by massive deposition of amorphous, acellular, eosinophilic, PAS-positive material within an enlarged lymph node. We report an unusual case of a 46-year-old female with a large abdominal lump in the left lumbar region with inguinal lymphadenopathy. Contrast-enhanced computed tomography (CECT) showed multiple variable-sized lobulated non-enhancing soft tissue attenuated masses showing multiple peripheral and central calcific foci in the right para-aortic, bilateral iliac region, pelvis on the left side and left inguinal region.
View Article and Find Full Text PDFBackground And Purpose: Morbidity and mortality of opportunistic fungal infections in COVID-19 patients are less studied and defined. The patients receiving immunosuppressive therapy, broad-spectrum antibiotics, corticosteroids, and invasive and non-invasive ventilation are the high-risk groups.
Materials And Methods: The demographic profile as well as clinical and radiological findings of all the patients with COVID-19 suspected of Mucormycosis (MM) were recorded.
Introduction: is an emerging pathogen that causes pulmonary mucormycosis.
Case Presentation: We report a case of pneumonia caused by in a 54-year-old type 2 diabetic patient. The organism was isolated from bronchoalveolar lavage fluid and preliminarily identified by fungal morphology and finally by sequencing of the internal transcribed spacer region.
The purpose of the current work is to determine how a magnetic field, nonlinear thermal radiation, a heat source or sink, a Soret, and activation energy affect bio-convective nanofluid flow across a Riga plate in terms of heat transfer qualities. The major goal of this investigation is to enhance the heat transfer rate. The flow problem is demonstrated in the form of a collection of PDEs.
View Article and Find Full Text PDFJ Cancer Res Ther
November 2022
Background: Cellular expression level of Breast Cancer-Associated Type 1 (BRCA1) encoded protein is the sign of genome integrity, stability, and surveillance. BRCA1 after sensing DNA damage activates repairing system and if mutated leaves genomic lesions unrepaired and triggers transformation of normal breast cells into cancerous ones.
Aims Of Study: We conducted in silico study to have a holistic view of BRCA1's correlation with multiple variables of breast invasive carcinoma.
Acute invasive fungal rhinosinusitis is a rare infection primarily affecting patients with co-morbidities like immunosuppression and poorly controlled diabetes. Mucormycosis is increasingly being reported in patients with SARS-CoV-2 (COVID-19). However, reports of coinfection of aspergillosis and mucormycosis involving nose, paranasal sinuses, orbit, and brain are rare in literature.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
July 2021
We report here a series of coordinatively-saturated and thermodynamically stable luminescent [Ln(dtntp)(HO)] [Ln(III) = Eu (1), Tb (2), Gd (3), Sm (4) and Dy (5)] complexes using an aminophenyl-terpyridine appended-DTPA (dtntp) chelating ligand as cell imaging and photocytotoxic agents. The N,N″-bisamide derivative of HDTPA named as dtntp is based on 4'-(4-aminophenyl)-2,2':6',2″-terpyridine conjugated to diethylenetriamine-N,N',N″-pentaacetic acid. The structure, physicochemical properties, detailed photophysical aspects, interaction with DNA and serum proteins, and photocytotoxicity were studied.
View Article and Find Full Text PDFThe present study was aimed to establish the First National Reference Standard (NRS) for Insulin lispro to allow stakeholders including manufacturer's laboratories, drug testing laboratories, drug regulatory authorities and academic institutions to demonstrate accuracy of the test results and to enable comparison and validation of analytical methods. The candidate standard for Insulin lispro was evaluated in a collaborative study to assign the vial content in order to serve it as NRS to support the Indian Pharmacopoeia (IP) monograph. The candidate standard was calibrated against the Ph.
View Article and Find Full Text PDFIndian J Endocrinol Metab
January 2018
Background: Menopause is associated with increased cardiovascular disease (CVD) risk. Arterial stiffness, a biomarker of vascular aging, increases the risk for CVD.
Aims And Objectives: The study was aimed to determine whether menopause is associated with arterial stiffness amongst natural and surgical menopausal women.
J Coll Physicians Surg Pak
August 2014
Objective: To determine the frequency and severity of facial nerve dysfunction following surgery for benign parotid gland tumours.
Study Design: A case series.
Place And Duration Of Study: ENT Department, Karachi Medical and Dental College and Abbasi Shaheed Hospital and Ziauddin University Hospital, from 1990 to 2010.
J Coll Physicians Surg Pak
August 2012
Follicular dendritic cell sarcoma is a very rare entity. So far only 12 cases have been reported world wide with involvement of tonsil. We present a new case of follicular dendritic cell sarcoma of the tonsil in a 52 years old woman with no evidence of neck node involvement.
View Article and Find Full Text PDFHydatid disease caused by Echinococcus granulosus is endemic in Indian subcontinent and a common surgical problem. Although hydatid cyst is common in the liver and lung, it can be encountered in almost every part of the body. Mediastinal hydatid disease is a rare occurrence and only a few cases have been reported in the literature.
View Article and Find Full Text PDFRenal artery pseudoaneurysm, although a well-known complication in patients after penetrating trauma or iatrogenic injury, has rarely been described after blunt torso trauma. A 22-year-old man suffered an accident while on a motorcycle. Upon arrival in the Emergency Room, the patient was unconscious, hypotensive and had hematuria.
View Article and Find Full Text PDFInt J Palliat Nurs
February 2003
This article reports on a questionnaire survey, which was conducted among health-care professionals to investigate their experience of opiate compliance in terminally ill patients with cancer pain. There were 93 respondents, ranging from hospital consultants to junior doctors and specialist nurses to staff nurses. Sixty-six respondents (71%) indicated that non-compliance was a problem in pain control.
View Article and Find Full Text PDF