A novel method for demonstrating cold agglutinin disease: a case report.

Background: Cold agglutinin disease is a rare disorder characterized by an autoimmune hemolytic anemia occurring at low temperatures. Physical examination findings, often limited to acrocyanosis, are combined with a thermal amplitude test to help establish the diagnosis. Thermal amplitude testing determines the highest temperature at which the cold agglutination will occur and is an important parameter in diagnosing cold agglutinin disease.

Characterization of Corneal Endothelial Injury During Penetrating Keratoplasty.

Purpose: To characterize corneal endothelial injury during penetrating keratoplasty in a controlled wet laboratory environment using human tissue. To identify potential areas or steps within surgery in which insult to the corneal endothelium may be most affected by trauma during routine penetrating keratoplasty.

Methods: Human donor corneas (n = 12) with intact endothelium underwent experimental penetrating keratoplasty.

Refractive index and its impact on pseudophakic dysphotopsia.

Purpose: It has been shown that the biggest dissatisfier for uncomplicated cataract surgery patients is pseudophakic dysphotopsia (PD). While edge design of an intraocular lens (IOL) impacts this problem, refractive index is still controversial as to its impact. This retrospective cohort study was designed to determine the role of increasing refractive index in PD.

Spectacle Independence after Cataract Extraction in Post-Radial Keratotomy Patients Using Hybrid Monovision with ReSTOR(®) Multifocal and TECNIS(®) Monofocal Intraocular Lenses.

Background: We report 2 patients who have undergone radial keratotomy (RK) preceding ReSTOR(®) multifocal intraocular lens (IOL; Alcon, Fort Worth, Tex., USA) implantation in their nondominant eyes and TECNIS(®) monofocal IOL (Abbott Medical Optics, Abbott Park, Ill., USA) in their dominant eyes.

Minus Piggyback Lens Overlaying ReSTOR(®) Multifocal Lens in High Myopia.

Background: We report the case of a 40-year-old female patient treated with implantation of the Acrysof® IQ ReSTOR® lens (Alcon, Fort Worth, Tex., USA) with overlaying Acrysof EXpand® minus piggyback lens (Alcon).

Methods: The patient had high myopia and was diagnosed with presbyopia and bilateral posterior subcapsular cataract.

Porcine lens nuclei as a model for comparison of 3 ultrasound modalities regarding efficiency and chatter.

Purpose: To validate a porcine lens model by comparing density and ultrasound (US) with known human standards using the Infiniti Ozil with Intelligent Phacoemulsification (torsional), Whitestar Signature Micropulse (longitudinal), and Ellips FX (transversal) modalities.

Setting: Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.

Development of a novel bioerodible dexamethasone implant for uveitis and postoperative cataract inflammation.

Delivery of anti-inflammatory steroids concurrently to both anterior and posterior segments of the eye is a challenge. The anterior ocular structures limit topical delivery. Injection can be disproportionately and repeatedly invasive and selective for only one ocular hemisphere.