Identification of Clinical Phenotypes in Septic Patients Presenting With Hypotension or Elevated Lactate.

Introduction: Targeted therapies for sepsis have failed to show benefit due to high variability among subjects. We sought to demonstrate different phenotypes of septic shock based solely on clinical features and show that these relate to outcome.

Methods: A retrospective analysis was performed of a 1,023-subject cohort with early septic shock from the ProCESS trial.